Archive | Ask Alconox

Cannabis Residue Cleaning: Quality Assurance in the Lab

Q. We are working on the laboratory testing and production of several cannabis products. We’ve been working with Alconox, Inc. products for some time to effectively clean our labware, glassware and processing equipment. What types of cleaning-related quality issues can you provide guidance on?

A. The medical cannabis, cannabidiol, hemp and similar industries are increasing in scope and interest, across the U.S. and the globe. Your question is timely. With FDA approval of some marijuana derived drugs, assurance that scientific innovation does not outpace Quality and Regulatory (QARA) guidelines is a concern for many.

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Posted in Articles, Ask Alconox, Biotechnology, Cannabis, Pharmaceutical, Quality/Regulatory0 Comments

Cleaning for Cosmetics Manufacturing: No Interference in Flavors and Fragrance

Q. Why are critical cleaners essential in flavor and fragrance industries? A. Many major flavor and fragrance companies use Alconox or Liquinox detergent to soak, scrub or sonicate their manufacturing equipment. The reason they use these detergents is that they are free of all flavors, fragrances, dyes, cationic biocides or disinfectants, and emollients that might leave residues. This way…

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Posted in Alcojet, Alconox, Ask Alconox, Citrajet, Cosmetic, Detojet, Food & Beverage, Liquinox, Ultrasonic0 Comments

Advanced Cleaning: Relationship Between Conductivity, Surface Tension and pH

Q: I am doing a conductivity study using Alconox detergent. I am seeing that the pH and Surface Tension listed on the COA differs between lots. Do you think these variables affect conductivity enough to alter my results?

A: Here’s the short answer… Surface tension does not have any interactive relationship with conductivity; pH has a very small, essentially negligible interaction with conductivity; and concentration and temperature are much bigger causes of change in conductivity.

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Choosing Temperature for Ultrasonic Parts Cleaning

Q. How to determine appropriate temperature to clean parts with ultrasonic cleaner?

A. In general, every 10 deg C you go up in temperature doubles the cleaning speed. The faster you want to clean the hotter you should get.

There is a theoretical optimal ultrasonic cavitation temperature at around 70 deg C depending on the exact concentration of detergent. Even though in theory cavitation…

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Posted in Ask Alconox, Laboratory, Manual Lab Cleaning, Medical Device, Metalworking & Precision Manufacturing0 Comments

Advanced Cleaning Mechanisms: What are Surfactant Systems?

Q. In your email you mentioned that Solujet and Citrajet have more sophisticated surfactant systems than a competitor’s low foaming washer detergent – could you explain a little bit more what ‘surfactant systems’ are?

A. Absolutely! Surfactants, or Surface Active Agents, are compounds that lower surface tension between particles, such as oil and water. In the oil and water example, a surfactant compound will contain hydrophilic and lipophilic molecules…

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Posted in Articles, Ask Alconox, Citrajet, Detergents, Solujet0 Comments

Detergent Color Variations

Q. The color of our Liquinox is slightly different by lot number. Why is this happening? Is there an issue, perhaps we have done something wrong with storage?  

A. Do not fear! These color variations are normal. There is a range of acceptable color differences in Liquinox detergent. Differences in the age and storage conditions of the raw materials and of the Liquinox detergent itself will account for differences in color

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Posted in Ask Alconox, Laboratory, Liquinox, Medical Device, Metalworking & Precision Manufacturing, Pharmaceutical0 Comments

Dilution Precision in Concentration Measurements

Q. Do I determine detergent dilution by weight or by volume or both?

A. In a laboratory setting, the most common method is to either make a weight/weight dilution (10-20 g Alconox detergent in 990 g of water), or a weight/volume dilution (10-20 g Alconox in 990 mL of water) for 1-2% solutions.  In manufacturing situations, often directions are written volume/volume or volume/weight.

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Posted in Alconox, Ask Alconox, Laboratory, Manual Lab Cleaning, Medical Device, Metalworking & Precision Manufacturing, Pharmaceutical0 Comments

Detergent Compatibility Information

Q. We have consulted your continuous exposure compatibility information for one of your detergents on various materials. We were wondering about the details of conditions used in formulating this documented info, such as temperature, detergent concentration and period of time in which these observations were made.

A. It is important to keep in mind that these documents are created for guidance and reference purposes and are based on our vast critical cleaning experience in laboratory and manufacturing settings.

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Posted in Articles, Ask Alconox, Detergents0 Comments

Cannabis Manufacturing Cleaning: Removing Cannabis Residue

Q: We are manufacturing cannabis products, legally, in California, but are struggling with cleaning cannabis residue. We cannot find any current Good Manufacturing Practice (cGMP) documentation to help us. Can you help us?

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Posted in Ask Alconox, Cannabis, Cosmetic, Detonox, Healthcare, Keylajet, Laboratory, Pharmaceutical0 Comments

Measuring Surface Tension without Tensiometer?

Q. Is there any way to “eyeball” surface tension to see if it’s dropping when roughly measuring concentration or bath life?  
A. To numerically measure surface tension, you need a tensiometer and this is the recommended method. Tensiometers come in many varieties including…

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