Archive | Manual Lab Cleaning

Removing PFOS and PFOA from Lab Glassware

Q. We need to remove perfluorooctanoic acid (PFOA) and perfluorooctyl sulfonate (PFOS) from laboratory glassware and stainless steel. Since they are inorganic residues, we’re using acidic cleaners, but are not finding them as effective as we expected. Any recommendations?
A. PFOS and PFOA are polar, anionic surfactants. They will best be cleaned by a high-emulsifying, anionic-surfactant-containing cleaner that can make mixed micelles to efficiently remove these residues from surfaces….

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Posted in Alconox, Ask Alconox, Laboratory, Manual Lab Cleaning0 Comments

Choosing Temperature for Ultrasonic Parts Cleaning

Q. How to determine appropriate temperature to clean parts with ultrasonic cleaner?

A. In general, every 10 deg C you go up in temperature doubles the cleaning speed. The faster you want to clean the hotter you should get.

There is a theoretical optimal ultrasonic cavitation temperature at around 70 deg C depending on the exact concentration of detergent. Even though in theory cavitation…

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Posted in Ask Alconox, Laboratory, Manual Lab Cleaning, Medical Device, Metalworking & Precision Manufacturing0 Comments

Removing Protein from Cell Culture Containers

Q: What do you recommend for removing protein from cell culture containers?
A. To clean cell culture containers and remove protein, use a freshly made solution of our enzymatic detergent….

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Posted in Biotechnology, Manual Lab Cleaning, Pharmaceutical, Tergazyme0 Comments

Monitoring Stability of Alconox Solution

Learn how to monitor stability of 1% Alconox Solution for proper storage.

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Posted in Alconox, Healthcare, Laboratory, Manual Lab Cleaning, Medical Device0 Comments

latex tubing

Can Alconox be used to clean latex?

Can Alconox powder be used to clean latex material (tubing)? Latex is inherently a product that naturally degrades via mechanisms of hardening, embrittling and cracking. However…

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Posted in Alconox, Manual Lab Cleaning, Nuclear0 Comments

Standard Operating Procedures for Cleaning

Q. What are important items to include in standard operating procedures for cleaning? A.  A large part of successful cleaning relies on having a sound, reproducible procedure. In general, a good SOP should present a list of materials and people involved, the surface being cleaned should be identified, and the eight key variables for cleaning […]

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Posted in Articles, Biotechnology, Detergents, Laboratory, Manual Lab Cleaning, Medical Device, Metalworking & Precision Manufacturing, Pharmaceutical0 Comments

Cleaning Proteins, RNA & DNA from Lab Equipment

Q. How can I clean proteins, RNA, and DNA from laboratory equipment?

A. Thank you for your question concerning cleaning proteins, RNA and DNA from laboratory equipment.

We will address each separately . . .

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Posted in Alconox, Citrajet, Citranox, Detojet, Laboratory, Manual Lab Cleaning, Tergazyme0 Comments

Cleaning for Tissue Culture Work

Q. I am doing tissue culture and having problems reliably growing cultures. I was told it may be my cleaning procedure. Can you help?

A. Clean interference-free glassware is necessary for successful tissue culture work. Upon consulting “Essential Procedures for Clinical Microbiology,” (Isenberg, H;: U of Michigan, ASM Press, 1998, 532) it was found…

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Posted in Laboratory, Liquinox, Manual Lab Cleaning0 Comments

BRK Cleanroom

Cleanroom Cleaning

We are in the process of building a cleanroom for medical device manufacturing. What detergents do you recommend? For cleanroom cleaning, we would recommend liquid concentrate detergents to…..

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Posted in Biotechnology, Liquinox, Manual Lab Cleaning, Medical Device, Pharmaceutical0 Comments

How to Clean Mold Release Agent from HDPE parts?

Q. We are looking for a product that will allow us to clean mold release agent from the surface of molded HDPE parts. A. The best way to reliably remove silicone based mold release agents is to immerse the HDPE parts in very hot (170ºF) 2% Alconox detergent followed by a very hot (170ºF) rinse, ideally both in ultrasonic tanks. After the first very hot rinse, normal ambient temperature rinsing can be done. This can also be done with stiff brushes, but of course protective equipment must be worn.

The theory behind this is that …

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Posted in Alconox, Detonox, Manual Lab Cleaning, Medical Device0 Comments