TechNotes

Q. It appears that the Solujet is leaving a ring on some of the labware that cannot be removed. What is this ring (sodium silicate?)? How do we remove it? The labware has not been completely submerged. We have just added the Solujet soak for some labware that may have stubborn organics. We have been giving the labware a 4 hour soak in 1% Solujet, followed by warm tap water rinse then wash with Liquinox followed by 3x DI rinse.

Click for the Answer.

Read the full story

Q. We have glassware that contains adhesive and API dissolved in organic solvents. If we do not do additional organic rinses prior to the aqueous rinses we have issues. Is there any way we can avoid the organic rinses?
A. To avoid organic rinses, you can soak in a high emulsifying cleaner such as a 1% Alconox solution (1.25 oz/gal or 10 g/L) prior to aqueous rinsing. Ideally soak in a warm or hot solution for fastest and most reliable results. The emulsifiers in Alconox will emulsify the solvents and active pharmaceutical ingredients (API). Be sure to rinse at the same temperature you are soaking at so you do not break the emulsion and redeposit the API or solvents. If you soak hot . . .

Read the full story

My question is related to a minimum detergent concentration.  We manually wash labware of all sizes in 0.3% Liquinox solution. We also pre-wash or pre-rinse the labware and control our parts load.  We rarely have failures. We want to change our protocol to extend the wash water use for one day instead of based on a numerical parts load.  Do you think a 0.3% Liquinox concentration is sufficient detergent capacity to go an entire day?

Read the full story

Q. How can I clean proteins, RNA, and DNA from laboratory equipment?

A. Thank you for your question concerning cleaning proteins, RNA and DNA from laboratory equipment.

We will address each separately . . .

Read the full story

Q: We are a large biotech and in an effort to go green with our cleaning, we are exploring cold cleaning (cleaning with cold water) using your detergents. A: Cold cleaning is a very reasonable approach for energy conservation, and in short, its effectiveness depends on the details of the application.

Read the full story

We are in the process of building a cleanroom for medical device manufacturing. What detergents do you recommend? For cleanroom cleaning, we would recommend liquid concentrate detergents to…..

Read the full story

Q. We are looking for a product that will allow us to clean mold release agent from the surface of molded HDPE parts. A. The best way to reliably remove silicone based mold release agents is to immerse the HDPE parts in very hot (170ºF) 2% Alconox detergent followed by a very hot (170ºF) rinse, ideally both in ultrasonic tanks. After the first very hot rinse, normal ambient temperature rinsing can be done. This can also be done with stiff brushes, but of course protective equipment must be worn.

The theory behind this is that …

Read the full story

What is the difference between Tergazyme and Alconox? Is one better? Is one more mild?

Read the full story

Learn how to clean endoscopes with an enzyme cleaner including shelf life monitoring tips to ensure active enzymes.

Read the full story

I am using reusable cell culture tubes for boiling urine samples at 121°C with 8M NaOH solution. After this application, there is a white stain inside, which I can’t scrub off. I used Alconox at the concentration on the container: 3-5 Tbsp/gal. I’ve soaked them, scrubbed them, and then also sonicated in a cold Alconox solution for 30 min….

Read the full story