TechNotes

Q. We are having foaming issues in ultrasonic cleaner. Basically, we are looking for a non-foaming version of the Liquinox cleaner we are currently using.  Can you use a detergent that doesn’t foam in an ultrasonic bath? A. Depending on what the foaming issue is, you may be able to continue using Liquinox detergent. As a general statement….

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How do we go about reducing foam suds in our 1% Liquinox ultrasonic bath? We have 3 ultrasonic tanks in our series process. Bath 1 has the 1% solution. Bath 2 and 3 are a rinsing cascade system with RO water only. The foam is building up in tank 1 and then transfers to tank 2.

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Q. How can I clean proteins, RNA, and DNA from laboratory equipment?

A. Thank you for your question concerning cleaning proteins, RNA and DNA from laboratory equipment.

We will address each separately . . .

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Q: You recently recommended Detonox detergent for a tough cleaning challenge we had. You rushed a sample over and it worked fantastically. I have review your technical bulletin, but is there anything else you can tell me about it? Is it better than Alconox and Liquinox? It seems great.

A: Thank you for the feedback and question…..

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As you likely know, the Ixef® PARA is part of polyamide family and, as such, has an inherent chemical resistance. While Ixef® compounds display a good resistance to chemical reagents, the amide function in the resin matrix makes them sensitive to certain chemicals. Therefore, we like to recommend….

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Q. What is the best way to monitor for bath life extension?
A.To avoid potential for cross contamination, only freshly made up cleaning solutions should be used for the highest levels of critical cleaning. In general, a pH change of 1 unit towards neutral indicates an exhausted cleaning solution. Bath life can be extended. Learn How.

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Several years ago, our plant was directed to use the Refractive Index as a method of letting us monitor bath concentration during ultrasonic cleaning with your Liquinox detergent. More recently, our factory in Asia switched to Liquinox and were directed to use a conductivity measurement to monitor concentration. I decided to measure our cleaning bath using both methods and found a discrepancy — the brix (Refractive Index) reading was slightly above 1% concentration, but the Conductivity reading was nearly 2% concentration.

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Q. What is the best way to clean LC/MS glassware?
A. We have published a whitepaper on the formal LC/MS glassware cleaning procedure. Contact us at cleaning@alconox.com for a copy.

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Q. Currently using Alconox, but are considering a switch to liquinox. We have seen less residuals with Liquinox, which is desireable. What are the recommendations and concerns with switching from Alconox to Liquinox? What are the difference in ingredients between the two?
A. Alconox and Liquinox are functionally equivalent cleaners, but are not chemically identical. Click to learn more and access the Liquinox and Alconox msds.

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What is the best way for removing wax from pipettes and glassware? The best way to clean wax and petrolatum from pipettes is to use very hot 1% solutions.

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