TechNotes

My question is related to a minimum detergent concentration.  We manually wash labware of all sizes in 0.3% Liquinox solution. We also pre-wash or pre-rinse the labware and control our parts load.  We rarely have failures. We want to change our protocol to extend the wash water use for one day instead of based on a numerical parts load.  Do you think a 0.3% Liquinox concentration is sufficient detergent capacity to go an entire day?

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Q. How can I clean proteins, RNA, and DNA from laboratory equipment?

A. Thank you for your question concerning cleaning proteins, RNA and DNA from laboratory equipment.

We will address each separately . . .

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Q: We are a large biotech and in an effort to go green with our cleaning, we are exploring cold cleaning (cleaning with cold water) using your detergents. A: Cold cleaning is a very reasonable approach for energy conservation, and in short, its effectiveness depends on the details of the application.

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We are in the process of building a cleanroom for medical device manufacturing. What detergents do you recommend? For cleanroom cleaning, we would recommend liquid concentrate detergents to…..

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Q. We are looking for a product that will allow us to clean mold release agent from the surface of molded HDPE parts. A. The best way to reliably remove silicone based mold release agents is to immerse the HDPE parts in very hot (170ºF) 2% Alconox detergent followed by a very hot (170ºF) rinse, ideally both in ultrasonic tanks. After the first very hot rinse, normal ambient temperature rinsing can be done. This can also be done with stiff brushes, but of course protective equipment must be worn.

The theory behind this is that …

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What is the difference between Tergazyme and Alconox? Is one better? Is one more mild?

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Learn how to clean endoscopes with an enzyme cleaner including shelf life monitoring tips to ensure active enzymes.

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I am using reusable cell culture tubes for boiling urine samples at 121°C with 8M NaOH solution. After this application, there is a white stain inside, which I can’t scrub off. I used Alconox at the concentration on the container: 3-5 Tbsp/gal. I’ve soaked them, scrubbed them, and then also sonicated in a cold Alconox solution for 30 min….

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Alcotabs® Tablet Pipet Detergent is a tablet that is designed to effervesce and give time release flotation and detergent cleaning in a siphon pipet washer. Alcotabs detergent dissolve to a pH near 7, starting out acidic and the pH rises as the effervescence slows down and eventually stops. The tablets contain anionic surfactants, phosphates, carbonates and organic acids.

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Q. Currently using Alconox, but are considering a switch to liquinox. We have seen less residuals with Liquinox, which is desireable. What are the recommendations and concerns with switching from Alconox to Liquinox? What are the difference in ingredients between the two?
A. Alconox and Liquinox are functionally equivalent cleaners, but are not chemically identical. Click to learn more and access the Liquinox and Alconox msds.

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