Archive | Pharmaceutical

CIP

Static and Dynamic Spray Balls for Clean in Place

Q. What are the differences between Static and Dynamic spray balls in CIP machines? A. The typical considerations in using either static or dynamic spray balls in CIP (clean-in-place) are that….

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Replacing Isopropyl Alcohol in Pharmaceutical Cleaning

Q. I’ve been told that we should no longer use isopropyl alcohol for cleaning our pharmaceutical equipment. What should we use instead?

A. In pharmaceutical cleaning applications, isopropyl alcohol (IPA) is less than ideal. Alcohol will clean residues which are soluble in alcohol, but that is a limited range.  Using critical cleaning, aqueous detergents are a far more robust and will allow for more effective cleaning processes.

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Advanced Cleaning Mechanisms: Detergency and Concentration

Intuition, logic, and maybe even some experiences, can lead us to believe more detergent is better.  These everyday experiences where it might apply include your washing machine, dishwasher, or even your hands in the bathroom sink.  But, what is actually meant by better?  This is where concentration and detergency come into play, terms you may see in our literature and documentation, as well as our responses and solutions to cleaning challenges.

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Posted in Articles, Biotechnology, Cosmetic, Electronic, Laboratory, Medical Device, Metalworking & Precision Manufacturing, Pharmaceutical0 Comments

How to: Remove Residual Silicone Oils

Q. We are currently using a solvent and we want to switch to a safer product, such as a water-based cleaner.  Do you have a detergent that can assist in the removal of residual silicone oils that are left in medical device mold inserts manufactured using clear rubber material?   Will Alconox detergent work as your web page says without ultrasonic?

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Are there any PFAS, PFOA, or PFOS in Alconox Inc. Critical Cleaners?

Q. Is there any PFOA or PFOS in any Alconox cleaner?
A. PFOA and PFOS are perfluoro-octanoic acid and perfluoro-octane sulfonate. None of the Alconox, Inc brand cleaners contains PFOA or PFOS ingredients.

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Posted in Electronic, Healthcare, Laboratory, Manual Lab Cleaning, Pharmaceutical0 Comments

See You in Chicago for Cphi North America

Visit Alconox Inc. at Cphi North America in Chicago, April 30 – May 2, 2019. Stop by Booth #2304 to receive our unique gifts, expert technical support for your critical cleaning applications, and detergent samples.

Our critical cleaning detergents remove an array of soils while leaving no interfering residues in Pharmaceutical applications.

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Join Us at Interphex NYC 2019

Visit Alconox, Inc. at Interphex in NYC, April 2-4, 2019. Stop by Booth #2226 to receive our unique gifts, expert technical support for your critical cleaning applications, and detergent samples. Our critical cleaning detergents remove an array of soils while leaving no interfering residues in Pharmaceutical and Biotech applications.

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Posted in Biotechnology, News, Pharmaceutical0 Comments

Cannabis Residue Cleaning: Quality Assurance in the Lab

Q. We are working on the laboratory testing and production of several cannabis products. We’ve been working with Alconox, Inc. products for some time to effectively clean our labware, glassware and processing equipment. What types of cleaning-related quality issues can you provide guidance on?

A. The medical cannabis, cannabidiol, hemp and similar industries are increasing in scope and interest, across the U.S. and the globe. Your question is timely. With FDA approval of some marijuana derived drugs, assurance that scientific innovation does not outpace Quality and Regulatory (QARA) guidelines is a concern for many.

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Posted in Articles, Ask Alconox, Biotechnology, Cannabis, Pharmaceutical, Quality/Regulatory0 Comments

Residue Detection: Swab Method

Q. Do you have a recommended swab detection method for residual detergent?

A. We most certainly do.  It is suggested to use a swabbing area of 5 cm X 5 cm. Where extreme low level acceptance criteria on a low recovery residue, i.e. some product residues, it can help to….

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Posted in Biotechnology, Detergents, Laboratory, Medical Device, Pharmaceutical, Validation0 Comments

Detergent Color Variations

Q. The color of our Liquinox is slightly different by lot number. Why is this happening? Is there an issue, perhaps we have done something wrong with storage?  

A. Do not fear! These color variations are normal. There is a range of acceptable color differences in Liquinox detergent. Differences in the age and storage conditions of the raw materials and of the Liquinox detergent itself will account for differences in color

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Posted in Ask Alconox, Laboratory, Liquinox, Medical Device, Metalworking & Precision Manufacturing, Pharmaceutical0 Comments