Archive | Pharmaceutical

Cannabis Residue Cleaning: Quality Assurance in the Lab

Q. We are working on the laboratory testing and production of several cannabis products. We’ve been working with Alconox, Inc. products for some time to effectively clean our labware, glassware and processing equipment. What types of cleaning-related quality issues can you provide guidance on?

A. The medical cannabis, cannabidiol, hemp and similar industries are increasing in scope and interest, across the U.S. and the globe. Your question is timely. With FDA approval of some marijuana derived drugs, assurance that scientific innovation does not outpace Quality and Regulatory (QARA) guidelines is a concern for many.

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Posted in Articles, Ask Alconox, Biotechnology, Cannabis, Pharmaceutical, Quality/Regulatory0 Comments

Biopharma Cleaning: Hormone Residue

Q. How can I clean residual hormone residue from our process lines and tanks?
A. For manual cleaning we would highly recommend TergazymeⓇ Enzyme Active Powered Detergent. It contains protein enzymes that can effectively break down protein based hormones along with powerful emulsifiers.

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Posted in Alcojet, Biotechnology, Detojet, Detonox, Laboratory, Pharmaceutical, Tergazyme0 Comments

Scale Removal from Stainless Parts

Q: Can Alconox Inc. recommend a detergent for scale removal from stainless parts in an ultrasonic? A: Sure can. The best scale removing detergent for manual cleaning of stainless steel parts is Citranox® Liquid Acid Cleaner and Detergent. Citranox detergent is a mild acid, high chelating detergent for high performance removal of metal oxides, scale, salts and inorganic residues in manual and ultrasonic cleaning. It is also corrosion inhibited and free rinsing for reliable results and no interfering residues.

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Posted in Citranox, Laboratory, Manual Lab Cleaning, Metalworking & Precision Manufacturing, Pharmaceutical0 Comments

Are there any PFAS, PFOA, or PFOS in Alconox Inc. Critical Cleaners?

Q. Is there any PFOA or PFOS in any Alconox cleaner?
A. PFOA and PFOS are perfluoro-octanoic acid and perfluoro-octane sulfonate. None of the Alconox, Inc brand cleaners contains PFOA or PFOS ingredients.

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Posted in Environmental, Healthcare, Laboratory, Manual Lab Cleaning, Pharmaceutical0 Comments

Pharmaceutical Cleaning: Insoluble Tablet Coating

Q. Water insoluble tablet coatings used for solid dose enteric pharmaceutical tablets are very difficult to clean from coating equipment. It was hard to validate the equipment and prevent cross contamination.

A. The use of hot 140 deg F 2% Citranox for manual cleaning allowed succesfull removal of water insoluble salts used in these coatings. The references in the Pharmaceutical Cleaning Validation References PDF will help you with validation. And if you have a question for our experts about critical cleaning, please visit Ask Alconox.

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Posted in Citranox, Pharmaceutical0 Comments

Manual Cleaning A 100 Gallon Mixer

Q: We are looking for detergent and process recommendations for manual cleaning of a 100 gallon mixer. We make one product in the mixer which contains water, starch, acidic buffers, sucralose and preservative. Currently when cleaning, we boil for 1 hour at 90°C, then cool, drain and soak in cool water while using the mixing blades.  Scrub brushes and a spray hosing follows that. The mixer is made from stainless steel.

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Posted in Alconox, Citranox, Food & Beverage, Liquinox, Pharmaceutical2 Comments

Join Us at ISPE 2019 Annual Meeting and Expo

Visit Alconox, Inc. at the ISPE 2019 Annual Meeting and Expo in Las Vegas, NV, October 27-30. Stop by Booth #101 to receive our unique gifts, expert technical support for your critical cleaning applications, and detergent samples.

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Posted in News, Pharmaceutical0 Comments

Advanced Cleaning Mechanisms: The Last to Rinse

Q. What does “detergent is the last to leave the equipment surface” after rinsing mean? This seems like a broad statement, can it be supported by literature/documentation?
A. The only source of “detergent last to rinse” that I am aware of is based on the physical behavior of surface active agents and the interchangeable use of the word detergent and surfactant in common usage. More properly you should say the surfactant is the last to rinse. Learn More about Surfactant.

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Posted in Detergents, Medical Device, Pharmaceutical0 Comments

Alconox detergents

Shelf Life of Opened Detergent Concentrate

Q. What is the shelf life of the Liquinox concentrate? A. Liquinox conforms to its 2 year shelf life under typical laboratory storage conditions…

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Posted in Detergents, Healthcare, Laboratory, Liquinox, Medical Device, Metalworking & Precision Manufacturing, Pharmaceutical, Validation0 Comments

Laboratory Cleaning: Removing Petrolatum and Wax

Which Alconox Inc. product do you recommend for removing petrolatum and paraffin from stainless steel, glassware, and plastics? We will be washing utensils and equipment by hand in the lab.

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Posted in Cosmetic, Detonox, Laboratory, Manual Lab Cleaning, Pharmaceutical0 Comments