Archive | Pharmaceutical

Removing Protein in Pharmaceutical and Biotech Manufacturing

Q. How do you remove protein out of pipes, centrifuges and tanks in a CIP environment with water temperatures averaging 20C?

A. In a cooler temperature environment, consider adding an enzymatic cleaner to your alkaline/acidic CIP routine. A product like Tergazyme® Enzyme-Active Powdered Detergent, which contains both protease and surfactants, is not only efficient at removing the biofilm, but will also slow down the formation of biofilm and allow the regular cleaning cycle to clean effectively for more cycles.

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Posted in Biotechnology, Pharmaceutical, Tergazyme0 Comments

Clean-in-place (CIP) with Citrajet Detergent

Q. Our pharmaceutical company is transferring product manufacture to a different one our facilities. We used a CIP cleaning process with Citrajet and are going to have to perform validation and verification tests again. What information do we need for our testing? Chemical properties might be helpful as well as the science on how this chemical works. We would also need information on disposal and the requirements for allowing this to flow to normal process drains.

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Posted in Citrajet, Keylajet, Pharmaceutical, Solujet, Validation0 Comments

Cold Cleaning

Q: We are a large biotech and in an effort to go green with our cleaning, we are exploring cold cleaning (cleaning with cold water) using your detergents. A: Cold cleaning is a very reasonable approach for energy conservation, and in short, its effectiveness depends on the details of the application.

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Posted in Biotechnology, Cosmetic, Laboratory, Manual Lab Cleaning, Medical Device, Metalworking & Precision Manufacturing, Pharmaceutical0 Comments

BRK Cleanroom

Cleanroom Cleaning

We are in the process of building a cleanroom for medical device manufacturing. What detergents do you recommend? For cleanroom cleaning, we would recommend liquid concentrate detergents to…..

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Posted in Biotechnology, Liquinox, Manual Lab Cleaning, Medical Device, Pharmaceutical0 Comments

Tergazyme and Alconox

Tergazyme vs. Alconox

What is the difference between Tergazyme and Alconox? Is one better? Is one more mild?

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Posted in Alconox, Biotechnology, Manual Lab Cleaning, Medical Device, Pharmaceutical, Tattoo, Tergazyme0 Comments

Cleaning Stressed Polycarbonate

Q. In the past you have recommended a specific detergent type detergent for our sensitive plastics (stressed polycarbonate), mentioning that it does not have a surfactant. Can you elaborate for us why?

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Posted in Biotechnology, Cosmetic, Detojet, Medical Device, Pharmaceutical0 Comments

Keylajet

What is Keylajet detergent?

We’ve been a long time user of Solujet for our CIP system, and love it! I recently passed by your booth at a tradeshow and you set me up with a sample of Keylajet when we mentioned some extra viscous waxy residue we were having trouble removing. We were hoping to stay with our CIP method. It worked great! Can you relay more info?

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Posted in Cosmetic, Detonox, Keylajet, Pharmaceutical, Solujet0 Comments

Bathocard

9 Steps to Successful Critical Cleaning: BATHOCARD

Q. Did you know there are nine different factors that determine successful cleaning? A. “BATHOCARD” a phrase coined by Alconox technical team.

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Posted in Biotechnology, Cosmetic, Detergents, Food & Beverage, Healthcare, Industry, Laboratory, Medical Device, Metalworking & Precision Manufacturing, Pharmaceutical, PhotovoltaicComments Off on 9 Steps to Successful Critical Cleaning: BATHOCARD

Detecting Residue in Cleaning Validation

When beginning cleaning validation, a company must identify the residues to be tested and then select the best detection method. Alconox Inc. is here to help. We provide validation service support

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Posted in Articles, Cosmetic, Medical Device, Pharmaceutical, Validation0 Comments

Alconox Liquinox

Differences between Alconox and Liquinox

Q. Currently using Alconox, but are considering a switch to liquinox. We have seen less residuals with Liquinox, which is desireable. What are the recommendations and concerns with switching from Alconox to Liquinox? What are the difference in ingredients between the two?
A. Alconox and Liquinox are functionally equivalent cleaners, but are not chemically identical. Click to learn more and access the Liquinox and Alconox msds.

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Posted in Alconox, Ask Alconox, Laboratory, Liquinox, Manual Lab Cleaning, Medical Device, Pharmaceutical, Validation0 Comments