Archive | Pharmaceutical

Ultrasonic with Low-Foam Detergent

Q. We are having foaming issues in ultrasonic cleaner. Basically, we are looking for a non-foaming version of the Liquinox cleaner we are currently using.  Can you use a detergent that doesn’t foam in an ultrasonic bath? A. Depending on what the foaming issue is, you may be able to continue using Liquinox detergent. As a general statement….

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Posted in Biotechnology, Healthcare, Laboratory, Liquinox, Manual Lab Cleaning, Medical Device, Pharmaceutical, Solujet0 Comments

Keylajet

What is Keylajet detergent?

We’ve been a long time user of Solujet for our CIP system, and love it! I recently passed by your booth at a tradeshow and you set me up with a sample of Keylajet when we mentioned some extra viscous waxy residue we were having trouble removing. We were hoping to stay with our CIP method. It worked great! Can you relay more info?

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Posted in Cosmetic, Detonox, Keylajet, Pharmaceutical, Solujet0 Comments

Pharmaceutical Cleaning: Choosing CIP Detergent  

Equipment used in pharmaceutical manufacturing must be cleaned before each use, and the cleaning procedure used must be in accordance with good manufacturing practices (GMPs). There are different types of CIP including, single pass systems and recirculation system. No matter which type is used, Alconox, Inc. provides support to meet cGMP regulations and detergents ideally suited for CIP systems.

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Posted in Citrajet, Pharmaceutical, Solujet0 Comments

Visit Us at Pack Expo 2018 with Comped Admission

Visit Alconox, Inc. at PACK EXPO International and Healthcare Packaging EXPO 2018, at McCormick Place in Chicago, October 14-17, 2018.  Mention Code: 72W43 for free registration to the event. 

Once at the show, stop by Booth W-803 to receive our unique gifts, expert technical support for your critical cleaning applications, and detergent samples.

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Posted in News, Pharmaceutical0 Comments

Using High Foam Detergent in an Automated Ultrasonic Cleaning Line

Q. Can we use high-foaming detergents in an automated cleaning line?
A. Yes, but using a high-foam detergent requires a rinse chamber that allows foam to rinse off and drain easily and completely. If the automated line uses initial spray rinsing right after the wash tank

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Posted in Citranox, Cosmetic, Liquinox, Medical Device, Pharmaceutical0 Comments

Detonox 1 gallon

What is Detonox detergent?

Q: You recently recommended Detonox detergent for a tough cleaning challenge we had. You rushed a sample over and it worked fantastically. I have review your technical bulletin, but is there anything else you can tell me about it? Is it better than Alconox and Liquinox? It seems great.

A: Thank you for the feedback and question…..

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Posted in Biotechnology, Cosmetic, Detonox, Manual Lab Cleaning, Medical Device, Pharmaceutical0 Comments

Cleaning Silicone Grease Residue Build Up in a Parts Washer

Q. Our parts washer uses a 2.5 hour cycle following a manual wash. A build up of silicone grease is observed. Our preference is to reduce manual cleaning. Is there a cleaning agent available that can remove silicone grease that would be compatible with a parts washer using water as the cleaning agent?

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Posted in Alcojet, Medical Device, Pharmaceutical, Solujet0 Comments

Monitoring Bath Life Extension in Medical Device Cleaning

Q. What is the best way to monitor for bath life extension?
A.To avoid potential for cross contamination, only freshly made up cleaning solutions should be used for the highest levels of critical cleaning. In general, a pH change of 1 unit towards neutral indicates an exhausted cleaning solution. Bath life can be extended. Learn How.

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Posted in Biotechnology, Cosmetic, Healthcare, Laboratory, Manual Lab Cleaning, Medical Device, Pharmaceutical0 Comments

Risk Based Limits and Pharmaceutical Cleaning

Q. We are moving from LD50 data to ADE (PDE) limits based on HBELs. This is allowing us to eliminate disposables for low-risk products.  How do I know which can be manually cleaned and which needs to be in a washer? Can manual cleaning be validated?

A. Many pharma and biotech companies have been moving to Health-Based Exposure Limits (HBELs) meaning Acceptable Daily Exposure (ADE) or Permitted Daily Exposure (PDE) limits as detergent residue limits.    

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Posted in Biotechnology, Pharmaceutical, Validation0 Comments

Alconox Liquinox

Differences between Alconox and Liquinox

Q. Currently using Alconox, but are considering a switch to liquinox. We have seen less residuals with Liquinox, which is desireable. What are the recommendations and concerns with switching from Alconox to Liquinox? What are the difference in ingredients between the two?
A. Alconox and Liquinox are functionally equivalent cleaners, but are not chemically identical. Click to learn more and access the Liquinox and Alconox msds.

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Posted in Alconox, Ask Alconox, Laboratory, Liquinox, Manual Lab Cleaning, Medical Device, Pharmaceutical, Validation0 Comments