Archive | Pharmaceutical

Clean in Place “Hacks” for Water Spots

A: A two-step cycle with a base followed by an acid, whether it be CIP cleaning or in a large scale liquid dispensing system washer, is a robust and, when needed, is a recommended process. Water spots typically occur because of two main mechanisms….

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Posted in Biotechnology, Citrajet, Cosmetic, Laboratory, Medical Device, Metalworking & Precision Manufacturing, Pharmaceutical, Solujet0 Comments

Going Green with Cold Cleaning

Q: We are a large biotech and in an effort to go green with our cleaning, we are exploring cold cleaning (cleaning with cold water) using your detergents. A: Cold cleaning is a very reasonable approach for energy conservation, and in short, its effectiveness depends on the details of the application.

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Posted in Biotechnology, Cosmetic, Laboratory, Manual Lab Cleaning, Medical Device, Metalworking & Precision Manufacturing, Pharmaceutical0 Comments

Cleaning Stressed Polycarbonate

Q. In the past you have recommended a specific detergent type detergent for our sensitive plastics (stressed polycarbonate), mentioning that it does not have a surfactant. Can you elaborate for us why?

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Posted in Biotechnology, Cosmetic, Detojet, Medical Device, Pharmaceutical0 Comments

Types of Surfactants

Types of Surfactants

Q. What are the different types of surfactants? A. Anionic surfactants, Nonionic surfactants, Cationic surfactants, Amphoteric surfactants.

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Posted in Detergents, Medical Device, Pharmaceutical0 Comments

What is a Surfactant?

Q. What is a surfactant? A. Surfactant is short for “surface active agent,” it is an organic molecule with a hydrophobic (water-hating/oil-loving) end and a hydrophilic (water-loving) end.

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Posted in Biotechnology, Detergents, Laboratory, Medical Device, Pharmaceutical, Validation0 Comments

CIP

Static and Dynamic Spray Balls for Clean in Place

Q. What are the differences between Static and Dynamic spray balls in CIP machines? A. The typical considerations in using either static or dynamic spray balls in CIP (clean-in-place) are that….

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Posted in Biotechnology, Citrajet, Cosmetic, Pharmaceutical, SolujetComments Off on Static and Dynamic Spray Balls for Clean in Place

What to choose: acid vs alkaline cleaner?

Q:  What are the differences between an acid vs alkaline cleaner? A:  There are some key difference in choosing the right cleaner for your cleaning needs; the ph of a detergent is one dividing line. Acidic cleaners are commonly used to brighten or etch metals and are effective at removing any mineral deposits or oxidation […]

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Posted in Alconox, Biotechnology, Citrajet, Citranox, Medical Device, Metalworking & Precision Manufacturing, PharmaceuticalComments Off on What to choose: acid vs alkaline cleaner?

Replacing Isopropyl Alcohol in Pharmaceutical Cleaning

Q. I’ve been told that we should no longer use isopropyl alcohol for cleaning our pharmaceutical equipment. What should we use instead?

A. In pharmaceutical cleaning applications, isopropyl alcohol (IPA) is less than ideal. Alcohol will clean residues which are soluble in alcohol, but that is a limited range.  Using critical cleaning, aqueous detergents are a far more robust and will allow for more effective cleaning processes.

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Tergazyme

Tergazyme Solution Shelf Life

Q. Do you have any suggestions about the shelf life of 1% Tergazyme solution?

A. Tergazyme solutions should be used within 8 hours of dissolving the powdered Tergazyme detergent in water. As dry powder, Tergazyme has excellent stability with a shelf life of 2 years from date of manufacture.

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Posted in Healthcare, Laboratory, Pharmaceutical, Tattoo, Tergazyme0 Comments

Advanced Cleaning Mechanisms: Detergency and Concentration

Intuition, logic, and maybe even some experiences, can lead us to believe more detergent is better.  These everyday experiences where it might apply include your washing machine, dishwasher, or even your hands in the bathroom sink.  But, what is actually meant by better?  This is where concentration and detergency come into play, terms you may see in our literature and documentation, as well as our responses and solutions to cleaning challenges.

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Posted in Articles, Biotechnology, Cosmetic, Electronic, Laboratory, Medical Device, Metalworking & Precision Manufacturing, Pharmaceutical0 Comments