Tag Archive | "biopharma"

Removing Protein in Pharmaceutical and Biotech Manufacturing

Q. How do you remove protein out of pipes, centrifuges and tanks in a CIP environment with water temperatures averaging 20C?

A. In a cooler temperature environment, consider adding an enzymatic cleaner to your alkaline/acidic CIP routine. A product like Tergazyme® Enzyme-Active Powdered Detergent, which contains both protease and surfactants, is not only efficient at removing the biofilm, but will also slow down the formation of biofilm and allow the regular cleaning cycle to clean effectively for more cycles.

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Posted in Biotechnology, Pharmaceutical, TergazymeComments (0)

Pharmaceutical Cleaning Validation – Residue Detection Method Selection

Q. What are the residue detection methods that can be used for cleaners? Does Alconox provide pharmaceutical validation information? A. A pharmaceutical cleaning validation involves residue detection method selection. Residue detection method selection for cleaners can involve specific methods for specific cleaner ingredients . . .

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Posted in Medical Device, PharmaceuticalComments (0)

CIP

How much CIP detergent needed?

Q: We are starting a new bioprocessing facility where we will be cleaning stainless steel tanks via a Clean-In-Place sprayball system? How do I approximate how much detergent I will need? We are considering Alcojet or Solujet, follow by an acidic rinse with Citrajet. Is this a good plan? Any advice? A: A good rule of thumb for tis you need about….

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Posted in Biotechnology, Citrajet, Cosmetic, Keylajet, Pharmaceutical, SolujetComments (0)