TechNotes

Q: We are starting a new bioprocessing facility where we will be cleaning stainless steel tanks via a Clean-In-Place sprayball system? How do I approximate how much detergent I will need? We are considering Alcojet or Solujet, follow by an acidic rinse with Citrajet. Is this a good plan? Any advice? A: A good rule of thumb for tis you need about….

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Q. We are a generic pharmaceutical manufacturer of Creams and Ointments. We are having difficulty cleaning equipment (specifically CIP) after making these types of products. We have been successful in cleaning 95% of our products using the alkaline detergent. We have couple of products that leave a white film after the cleaning cycles. These products do not contain metal oxides. We are planning to try the Citranox acid cleaner. Any suggestions?

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Solujet cleaner is the detergent to consider for your next new pharmaceutical cleaning project or when you want to take the opportunity to improve when you are revalidating your existing cleaning system.

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We have a glass wash machine and use Alcojet for it. We would like to know if you need to include a neutralizing agent like Citrajet as part of the wash cycle (acid rinse)? Alcojet® Low Foaming Powdered Detergent is what we would call free-rinsing, meaning it rinses completely away with water without rinse aids.

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Residual titanium dioxide (TiO2) can certainly pose issues due to it’s nature in the presence of heat. To remove TiO2 from tanks using CIP sprayballs, it is important to use….

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Q. For cosmetic cleaning, how do we get toothpaste from mixing tank?
A. Use hot water, ~140 F, with Solujet low foaming cleaner if CIP or Liquinox high emulsifier if immersion cleaning is used. If latter is used, we recommend moderate agitation be used by turning on mixing blades.

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