TechNotes

Q. Our pharmaceutical company is transferring product manufacture to a different one our facilities. We used a CIP cleaning process with Citrajet and are going to have to perform validation and verification tests again. What information do we need for our testing? Chemical properties might be helpful as well as the science on how this chemical works. We would also need information on disposal and the requirements for allowing this to flow to normal process drains. Any help you can provide is appreciated.

A. Here are some key pieces of information you should find helpful, in addition to our SDS and technical bulletin downloads, when Cleaning in Place with Citrajet® Low Foaming Liquid Acid Cleaner.

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We’ve been a long time user of Solujet for our CIP system, and love it! I recently passed by your booth at a tradeshow and you set me up with a sample of Keylajet when we mentioned some extra viscous waxy residue we were having trouble removing. We were hoping to stay with our CIP method. It worked great! Can you relay more info?

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Residual titanium dioxide (TiO2) can certainly pose issues due to it’s nature in the presence of heat. To remove TiO2 from tanks using CIP sprayballs, it is important to use….

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Q: We are starting a new bioprocessing facility where we will be cleaning stainless steel tanks via a Clean-In-Place sprayball system? How do I approximate how much detergent I will need? We are considering Alcojet or Solujet, follow by an acidic rinse with Citrajet. Is this a good plan? Any advice? A: A good rule of thumb for tis you need about….

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Q. We are a generic pharmaceutical manufacturer of Creams and Ointments. We are having difficulty cleaning equipment (specifically CIP) after making these types of products. We have been successful in cleaning 95% of our products using the alkaline detergent. We have couple of products that leave a white film after the cleaning cycles. These products do not contain metal oxides. We are planning to try the Citranox acid cleaner. Any suggestions?

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Solujet cleaner is the detergent to consider for your next new pharmaceutical cleaning project or when you want to take the opportunity to improve when you are revalidating your existing cleaning system.

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We have a glass wash machine and use Alcojet for it. We would like to know if you need to include a neutralizing agent like Citrajet as part of the wash cycle (acid rinse)? Alcojet® Low Foaming Powdered Detergent is what we would call free-rinsing, meaning it rinses completely away with water without rinse aids.

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Q. For cosmetic cleaning, how do we get toothpaste from mixing tank?
A. Use hot water, ~140 F, with Solujet low foaming cleaner if CIP or Liquinox high emulsifier if immersion cleaning is used. If latter is used, we recommend moderate agitation be used by turning on mixing blades.

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