Alconox Blog: TechNotes

Q. I’ve been told that we should no longer use isopropyl alcohol for cleaning our pharmaceutical equipment. What should we use instead?

A. In pharmaceutical cleaning applications, isopropyl alcohol (IPA) is less than ideal. Alcohol will clean residues which are soluble in alcohol, but that is a limited range.  Using critical cleaning, aqueous detergents are a far more robust and will allow for more effective cleaning processes.

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Q: How can we clean residual deodorant from our stainless steel tanks? It is proving very difficult. It is largely AlCl3.

A: Deodorant, designed to stay in place for obvious reasons, can be quite adherent on processing equipment. If it stays on skin for extended periods, which is designed to avoid residues, imagine what it does to stainless steel!

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Mike Auerbach, Editor and Chief of American Pharmaceutical Review, spoke to Michael Moussourakis, Senior Director, Strategic Affairs at Alconox Inc. They discussed the unique cleaning challenges facing Pharmaceutical, Cosmetic and Cannabis manufacturers and the innovative solutions offered by Alconox Inc.   Auerbach: I understand Alconox has gotten into some sticky situations lately. Can you tell […]

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Meet cGMP regulations and stringent cleaning validation standards with CIP detergents from Alconox Inc. Whether you use single pass or recirculation systems, Alconox can provide a detergent ideally suited for your CIP system. Click to watch our latest video to learn best practices for Clean in Place and how to choose the right CIP detergent for your application.

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Q. How can I clean residual hormone residue from our process lines and tanks?
A. For manual cleaning we would highly recommend TergazymeⓇ Enzyme Active Powered Detergent. It contains protein enzymes that can effectively break down protein based hormones along with powerful emulsifiers.

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Q: We are looking for detergent and process recommendations for manual cleaning of a 100 gallon mixer. We make one product in the mixer which contains water, starch, acidic buffers, sucralose and preservative. Currently when cleaning, we boil for 1 hour at 90°C, then cool, drain and soak in cool water while using the mixing blades.  Scrub brushes and a spray hosing follows that. The mixer is made from stainless steel.

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Alconox Inc. will be at Pack Expo and Healthcare Packaging Expo 2019 at the Las Vegas Convention Center, September 23-25, 2019. Mention Code: 71P66 for free registration to the event.

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Visit Alconox Inc. at Cphi North America in Chicago, April 30 – May 2, 2019. Stop by Booth #2304 to receive our unique gifts, expert technical support for your critical cleaning applications, and detergent samples.

Our critical cleaning detergents remove an array of soils while leaving no interfering residues in Pharmaceutical applications.

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Visit Alconox, Inc. at Interphex in NYC, April 2-4, 2019. Stop by Booth #2226 to receive our unique gifts, expert technical support for your critical cleaning applications, and detergent samples. Our critical cleaning detergents remove an array of soils while leaving no interfering residues in Pharmaceutical and Biotech applications.

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Equipment used in pharmaceutical manufacturing must be cleaned before each use, and the cleaning procedure used must be in accordance with good manufacturing practices (GMPs). There are different types of CIP including, single pass systems and recirculation system. No matter which type is used, Alconox, Inc. provides support to meet cGMP regulations and detergents ideally suited for CIP systems.

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