TechNotes

Q. I’ve been told that we should no longer use isopropyl alcohol for cleaning our pharmaceutical equipment. What should we use instead?

A. In pharmaceutical cleaning applications, isopropyl alcohol (IPA) is less than ideal. Alcohol will clean residues which are soluble in alcohol, but that is a limited range.  Using critical cleaning, aqueous detergents are a far more robust and will allow for more effective cleaning processes.

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Q: We are looking for detergent and process recommendations for manual cleaning of a 100 gallon mixer. We make one product in the mixer which contains water, modified food starch, acidic buffers, sucralose and preservative. Currently when cleaning, we boil for 1 hour at 90°C, then cool, drain and soak in cool water while using the mixing blades.  Scrub brushes and a spray hosing follows that. The mixer is made from stainless steel.

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Visit Alconox Inc. at Cphi North America in Chicago, April 30 – May 2, 2019. Stop by Booth #2304 to receive our unique gifts, expert technical support for your critical cleaning applications, and detergent samples.

Our critical cleaning detergents remove an array of soils while leaving no interfering residues in Pharmaceutical applications.

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Visit Alconox, Inc. at Interphex in NYC, April 2-4, 2019. Stop by Booth #2226 to receive our unique gifts, expert technical support for your critical cleaning applications, and detergent samples. Our critical cleaning detergents remove an array of soils while leaving no interfering residues in Pharmaceutical and Biotech applications.

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Equipment used in pharmaceutical manufacturing must be cleaned before each use, and the cleaning procedure used must be in accordance with good manufacturing practices (GMPs). There are different types of CIP including, single pass systems and recirculation system. No matter which type is used, Alconox, Inc. provides support to meet cGMP regulations and detergents ideally suited for CIP systems.

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Visit Alconox, Inc. at PACK EXPO International and Healthcare Packaging EXPO 2018, at McCormick Place in Chicago, October 14-17, 2018.  Mention Code: 72W43 for free registration to the event. 

Once at the show, stop by Booth W-803 to receive our unique gifts, expert technical support for your critical cleaning applications, and detergent samples.

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Q: Can you tell me if Liquinox can clean/remove pharmaceutical probiotics? We use this product to clean our packaging lines. We have a customer who is looking to have us package their probiotic product.

A: Liquinox® Critical Cleaning Liquid Detergent is an excellent emulsifier of organic and oily residues. It will do the job. Best practice, however, would be to incorporate a powerful emulsifier of organic and oily residues, along with enhanced protein removal. 

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See Alconox, Inc. at Interphex in NYC, April 17-19, 2018. Stop by Booth #2226 to receive our unique gifts, expert technical support for your critical cleaning applications, and detergent samples.

Our critical cleaning detergents remove an array of soils while leaving no interfering residues in Pharmaceutical and Biotech applications. To learn more about the specific cleaning applications we can take on in the Pharmaceutical, Biotech Industries, click over to our website.

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We are cleaning a V Mixer made of NSF Stainless steel and we are using it to mix different protein powders, amino acids, and herbs for dietary supplements. It is small enough to be cleaned by hand but not small enough for any type of sink. I was advised to buy your Citranox product. Is that the best detergent for this job?  

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Q. We manufacture vitamins, which include minerals (calcium, magnesium etc.) and have found that Citranox is very effective in cleaning the residue left in our equipment. Unfortunately, we have learned that the pH of Citranox is too low for our local requirements. Do you have another detergent with a higher pH that would work equally as well?

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