Archive | Medical Device

Ensuring Accurate Formulation of Liquinox Detergent

Q. I am a validation manager and we use Liquinox in multiple pieces of equipment across our manufacturing site. While witnessing our cleaning, I noticed the dilution instructions are not being followed. Instead, operators are adding some squirts/pumps/pours from the bottle into a bucket with purified water. Does Liquinox have a range of effective concentration?  Do you have auto-mix ideas or other dosing solutions for customers facing this issue of accurate formulation?

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Posted in Biotechnology, Cosmetic, Liquinox, Medical Device, Pharmaceutical0 Comments

Do Enzymatic Detergents, Like Tergazyme Cleaner, Disinfect?

Q. I’m a Ph.D. student and I’m studying protein interactions. We have been using Tergazyme to clean lenses and cuvettes for our light scattering equipment and it works flawlessly! My question is: Does Tergazyme enzyme detergent have any disinfection properties, like killing of bacteria such as E. coli?

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Posted in Food & Beverage, Laboratory, Medical Device, Pharmaceutical, Tergazyme0 Comments

Water Spots on Stainless? Improve Blowing Process

Q. White spots appear on our stainless steel parts the day after cleaning with Alconox. Right after we clean them, they are dry and visually clean. So, is this next-day residue from the Alconox detergent? If not, can you tell us why this is happening? A. It is fairly unlikely that visually clean parts have Alconox residues suddenly appearing the next day.  In addition to Alconox being free rinsing, any residue that did not get rinsed for whatever reason, would be visible fairly immediately.

Most people in similar situations, even though the parts appear “dry and visually clean,” find that the spots are from water.

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Posted in Alconox, Biotechnology, Foodservice, Healthcare, Laboratory, Manual Lab Cleaning, Medical Device, Metalworking & Precision Manufacturing, Pharmaceutical0 Comments

How Does Tergazyme Enzyme Detergent Work?

Q:  You recently sent a sample of Tergazyme detergent for a tough cleaning challenge and it worked better than anything we had previously tried. I realize this must be due to the enzyme component. What information can you provide me on how enzyme detergents work, so I can share it with our decision makers / executives who want to better understand why this detergent got such different results?

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Posted in Biotechnology, Foodservice, Healthcare, Laboratory, Manual Lab Cleaning, Medical Device, Pharmaceutical, Tattoo, Tergazyme0 Comments

DI Water Wettability

Medical Device Cleaning – Rinsing Silicone O-rings

Q. I would like to know if our rinsing process (Ultrasonic Cleaning with Sterile distilled water for 10 minutes) is appropriate for rinse off. Parts we are cleaning: 150″ Silicone O-Rings.
A. Thanks for your question about the sufficiency of a 10 min. distilled water rinse in ultrasonics for cleaning medical device related silicon o-rings. Distilled water is generally fine for rinsing. The best rinse is …

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Posted in Medical Device0 Comments

Passivate: Citric Acid Option with Citranox and Citrajet Detergents

Surface contamination interferes with formation of protective oxide coating on stainless steel thereby leaving it open to corrosion. The stainless steel needs passivation.

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Posted in Citrajet, Citranox, Medical Device0 Comments

Cold Cleaning

Q: We are a large biotech and in an effort to go green with our cleaning, we are exploring cold cleaning (cleaning with cold water) using your detergents. A: Cold cleaning is a very reasonable approach for energy conservation, and in short, its effectiveness depends on the details of the application.

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Posted in Biotechnology, Cosmetic, Laboratory, Manual Lab Cleaning, Medical Device, Metalworking & Precision Manufacturing, Pharmaceutical0 Comments

BRK Cleanroom

Cleanroom Cleaning

We are in the process of building a cleanroom for medical device manufacturing. What detergents do you recommend? For cleanroom cleaning, we would recommend liquid concentrate detergents to…..

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Posted in Biotechnology, Liquinox, Manual Lab Cleaning, Medical Device, Pharmaceutical0 Comments

How to Clean Mold Release Agent from HDPE parts?

Q. We are looking for a product that will allow us to clean mold release agent from the surface of molded HDPE parts. A. The best way to reliably remove silicone based mold release agents is to immerse the HDPE parts in very hot (170ºF) 2% Alconox detergent followed by a very hot (170ºF) rinse, ideally both in ultrasonic tanks. After the first very hot rinse, normal ambient temperature rinsing can be done. This can also be done with stiff brushes, but of course protective equipment must be worn.

The theory behind this is that …

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Posted in Alconox, Detonox, Manual Lab Cleaning, Medical Device0 Comments

Medical Device Cleaning: Soft Acrylic Intraocular Lenses (IOLs)

Q: We are cleaning both hydrophilic and hydrophobic acrylic polymers. The cleaning process we use is mostly manual, involves no extended soaking, rather short contact with rubbing, and/or usage in an ultrasonic bath. Which of your products — Alconox, Tergazyme or Liquinox — would be most suitable for the cleaning of soft acrylic intraocular lenses (IOLs)?

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Posted in Liquinox, Medical Device, Optical0 Comments