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Swab limit for cleaning validation

Q. How do you calculate the swab limit, once it has been extracted in solution?
A. In general the swab limit for cleaning validations calculations go as follows:

Scientist chemist in gloves pouring detergent from flask into glass closeup

Using Concentrated Detergent Directly

Q: For ease of use, we would like to use the concentrated detergent in our lab directly, then add water.  Any issues with that?

A:  For Alconox Inc. manufactured detergents intended for manual / clean out of place use, we recommend making prior dilutions for usage of the detergents with known concentrations. However, an alternative would be to add a small amount of detergent concentrate (powder or liquid)….

Female gynecologist with a speculum in her hand

Using Tergazyme To Clean Speculums

Q: What is the right way to use Tergazyme to clean speculums?

A: This is a vital part of Healthcare and Medical Device instrument reprocessing and re-use, whether it is a speculum or related equipment including forceps, scalpel handles, trocars, etc.  The below typical questions are addressed in the following TechNote….

Vacuum Cyclic Nucleation

Types of Detergents for Vacuum Cyclic Nucleation (VCN)

Q: I just read your article on complex geometry 3d prints and it suggests using Luminox in conjunction with the VCN process.  Should I be using Luminox over current detergents we purchase from you? A: Thanks so much for your email and interest in work we do in 3D printing.  The experimental and testing work done that is discussed in….


Detergent Residue Interaction with Ketones and Solvents?

Q: We currently use Alconox to clean glassware at our facility. Do you have any studies showing potential Alconox detergent residue interaction with organic ketones and/or other organic solvents?

The short answer is that Alconox detergent, like all Alconox Inc. detergent products, are designed to be completely free-rinsing.  Therefore leaving no residues to speak of.  However, incomplete rinsing can of course happen. So this verification is important.  


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