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Pharmaceutical Cleaning Validation

Cleaning Validation: Detecting Trace Residues

Q. How do I find an analytical method to detect trace residues of Alconox brand cleaners for a cleaning validation?
A. The best place to find analytical methods for detergent residue detection for either a pharmaceutical or medical device cleaning validation is by downloading our Pharmaceutical Cleaning Validation document.

Density of Alconox Detergent

Q. Do you have the density of the Alconox detergent?
A. Thanks for your request for Alconox density. Alconox is a hygroscopic dry blended powder with a density that varies with settling and humidity. The density of Alconox varies from 0.85 g/mL to 1.1 g/mL, with a typical density of 0.95 g/mL.
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Citranox

Comparing Citranox to Citric Acid

Q. Is Citranox comparable to citric acid?

A. Yes, 1% Citranox® Liquid Acid Cleaner and Detergent can be used to replace the kind of cleaning achievable from 1% citric acid. The Citranox cleaner formulation is approximately 1/3 citric and other organic acids by weight…. Learn more

Cleaning Machine Oil with Liquinox

Q. We are cleaning straight machine oil off parts, followed by a Ozonics 203 dip. We have a vapor degreaser but stopped using it due to odors & EPA exhaust concerns. I plan to use Liquinox in a strong concentration to remove the residual oil and Ozonics 203. I plan to use the degreaser as a heated ultrasonic cleaner. What concentration would you recommend? This would be followed by our final u.s. cleaning using 2% Liquinox & dual cascading D.I. water.

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Aqueous Detergent Selection

Q. What are the key considerations when selecting an aqueous cleaning detergent?

A. Critical cleaning requires careful selection of cleaning chemistry and methods to ensure adequate performance without sacrificing either work safety or benign environmental impact. Key considerations include: Type of substrate, Type of soil, part complexity, level of cleanliness required, manufacturing process, cleaning efficiency, environmental consideration.
Learn more by downloading The Alconox Product Catalog and Detergent Selection Guide.

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For further assistance please fill out the form at Ask Alconox or email us at cleaning@alconox.com.