Industry

Q. Water insoluble tablet coatings used for solid dose enteric pharmaceutical tablets are very difficult to clean from coating equipment. It was hard to validate the equipment and prevent cross contamination.

A. The use of hot 140 deg F 2% Citranox for manual cleaning allowed succesfull removal of water insoluble salts used in these coatings. The references in the Pharmaceutical Cleaning Validation References PDF will help you with validation. And if you have a question for our experts about critical cleaning, please visit Ask Alconox.

Q: We are looking for detergent and process recommendations for manual cleaning of a 100 gallon mixer. We make one product in the mixer which contains water, starch, acidic buffers, sucralose and preservative. Currently when cleaning, we boil for 1 hour at 90°C, then cool, drain and soak in cool water while using the mixing blades.  Scrub brushes and a spray hosing follows that. The mixer is made from stainless steel.

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As with all critical cleaning applications, the need for effective, free-rinsing detergents is ever-present. The developing cannabis manufacturing industry is no exception. We’re here to help with removing cannabis resin from manufacturing equipment, sensitive glass, irrigation lines, and more.

We currently use Alconox detergent to clean our cold-form extruders. While it’s great for grease, it doesn’t seem to help cut the stickiness we see from cane molasses and corn syrup. Do you have a recommendation for another cleaning agent?