Cleaning Validation
Q. What is involved in a cleaning validation? Does Alconox provide information or support for validation? A. A cleaning validation is a documented guarantee that cleaning can be performed reliably and repeatedly to meet a predetermined level of cleanliness.
Pharmaceutical Testing – Oral Toxicity
Q. How is Oral Toxicity defined and reported? A. Pharmaceutical testing for Oral toxicity is reported as an Oral LD50, the lethal dose at which 50 percent of a population of animals will die when exposed orally.
Phosphate Free Critical Cleaning Detergents
Q. Which Alconox detergents are phosphate-free? A. Alconox supplies several phosphate-free critical cleaning detergents.
Cleaning Basal Media in a Large Tank
Q. Could you please recommend a minimum Solujet concentration, temperature and time for use with a CIP system to wash a large mixing tank dedicated to manufacturing DMEM-F12 basal media.
A. Without actually doing a study with your exact sprayballs and flow rates, I cannot give you precise time, temperatures and concentrations. I can give you some guidelines based on general experience with medical device cleaning validation.
Medical Device Cleaning: 17-4PH Stainless Steel
Q. A great deal or our instruments are manufactured from 17-4PH Stainless Steel. Our cleaning technician claims this material is corroding. I read the rinsing information recomending using a lower temperature for the 1% Alconox mixture. Is this a common issue with 17-4PH and are we using the wrong cleaning product or missing something?