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Cleaning Protein in Pharmaceutical and Biotech Manufacturing

Q. How do you remove protein out of pipes, centrifuges and tanks in a CIP environment with water temperatures averaging 20C?

A. In a cooler temperature environment, consider adding an enzymatic cleaner to your alkaline/acidic CIP routine. A product like Tergazyme® Enzyme-Active Powdered Detergent, which contains both protease and surfactants, is not only efficient at removing the biofilm, but will also slow down the formation of biofilm and allow the regular cleaning cycle to clean effectively for more cycles.

Pharma Ointment Residue via CIP Detergent

Q. We are a generic pharmaceutical manufacturer of Creams and Ointments. We are having difficulty cleaning equipment (specifically CIP) after making these types of products. We have been successful in cleaning 95% of our products using the alkaline detergent. We have couple of products that leave a white film after the cleaning cycles. These products do not contain metal oxides. We are planning to try the Citranox acid cleaner. Any suggestions?

Pharmaceutical Cleaning: Solujet for CIP Detergent

Solujet cleaner is the detergent to consider for your next new pharmaceutical cleaning project or when you want to take the opportunity to improve when you are revalidating your existing cleaning system.

Addition of Acid Rinse to Wash Cycle

We have a glass wash machine and use Alcojet for it. We would like to know if you need to include a neutralizing agent like Citrajet as part of the wash cycle (acid rinse)? Alcojet® Low Foaming Powdered Detergent is what we would call free-rinsing, meaning it rinses completely away with water without rinse aids.

Alconox Brands for Clean-In-Place (CIP) Systems

Q. What Alconox brand cleaners are recommended for Clean-In-Place (CIP) systems? What information does Alconox offer to assist in validating CIP cleaners? A. It is desirable to use a low

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