Archive | Biotechnology

How to: Clean and Disinfect for Viruses and Other Pathogens

Per Center for Disease Control (CDC) guidelines for cleaning and disinfecting viruses and other pathogens, any form of disinfection necessarily follows cleaning.  The process of cleaning will remove any residues that might shield any virus or pathogen from the disinfection step that comes next.  Disinfection, following the thorough cleaning and rinsing, can be done with bleach solutions….

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Posted in Biotechnology, Healthcare, Laboratory0 Comments

Supply Chain Management

Q: We are a mid-sized medical device company and are looking at reviewing and optimizing our supply chain.  Our goal is to move towards a culture of risk mitigation of our raw materials.  As a consumer of your detergents, what is Alconox Inc. doing to ensure consistent supply chain?

A: Thank you for the question as it is both important, and certainly an area of deserved focus and scrutiny from regulatory bodies.  Ensuring a continuous supply of drug, medical device or laboratory products requires a dependable supply of raw materials….

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Posted in Biotechnology, Cosmetic, Detergents, Food & Beverage, Foodservice, Healthcare, Laboratory, Medical Device, Pharmaceutical0 Comments

Coverall

Cleaning Coveralls and Other Potentially Contaminated PPE

Q: Can we use the Alconox Inc. detergents for washing to clean and disinfect coveralls for re-use?  We have Alconox powder in stock.

A:  Yes!  I would use the word clean as opposed to disinfect.  That is what aqueous detergents do. See these important links….

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Posted in Biotechnology, Healthcare, Medical Device, Pharmaceutical0 Comments

Clean Before Sterilization (Disinfection)

Did you know? If It’s Not Clean, You Can’t Sterilize.

Why must instruments be cleaned before being sterilized? According to the CDC, “Cleaning should precede all disinfection and sterilization processes.Cleaning involves the removal of debris (organic or inorganic) from an instrument or device. If visible debris is not removed, it will interfere with microbial inactivation and can compromise the disinfection or sterilization process.”

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Posted in Biotechnology, Food & Beverage, Foodservice, Healthcare, Laboratory, Manual Lab Cleaning, Medical Device, Pharmaceutical, Tattoo0 Comments

Replacing Isopropyl Alcohol in Cleaning

Q. I’ve been told that we should no longer use isopropyl alcohol for cleaning our pharmaceutical equipment. What should we use instead?

A. In pharmaceutical cleaning applications, isopropyl alcohol (IPA) is less than ideal. Alcohol will clean residues which are soluble in alcohol, but that is a limited range.  Using critical cleaning, aqueous detergents are a far more robust and will allow for more effective cleaning processes.

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Posted in Biotechnology, Healthcare, Medical Device, Pharmaceutical0 Comments

Cleaning pH Probes & Dissolved Oxygen Probes

Q. Which Alconox Inc. brand cleaner is well suited for cleaning pH and dissolved oxygen probes?

A. Dissolved oxygen and pH probes used in fermentation vessels can get buildup from the fermentation media that degrades the probe performance and increases the likelihood of batch to batch contamination. Even CIP systems cannot always reliably clean the port crevices and o-rings.

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Posted in Biotechnology, Food & Beverage, Laboratory, Tergazyme0 Comments

How Does Tergazyme Enzyme Detergent Work?

Q:  You recently sent a sample of Tergazyme detergent for a tough biologic cleaning challenge and it worked better than anything we had previously tried. I realize this must be due to the enzyme component. What information can you provide me on how enzyme detergents work, so I can share it with our decision makers / executives who want to better understand why this detergent got such different results?

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Posted in Biotechnology, Foodservice, Healthcare, Laboratory, Manual Lab Cleaning, Medical Device, Pharmaceutical, Tattoo, Tergazyme0 Comments

How to Choose a CIP Detergent

Meet cGMP regulations and stringent cleaning validation standards with CIP detergents from Alconox Inc. Whether you use single pass or recirculation systems, Alconox can provide a detergent ideally suited for your CIP system. Click to watch our latest video to learn best practices for Clean in Place and how to choose the right CIP detergent for your application.

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Posted in Biotechnology, Cosmetic, Pharmaceutical, Quality/Regulatory, Video0 Comments

Cannabis Residue Cleaning: Quality Assurance in the Lab

Q. We are working on the laboratory testing and production of several cannabis products. We’ve been working with Alconox, Inc. products for some time to effectively clean our labware, glassware and processing equipment. What types of cleaning-related quality issues can you provide guidance on?

A. The medical cannabis, cannabidiol, hemp and similar industries are increasing in scope and interest, across the U.S. and the globe. Your question is timely. With FDA approval of some marijuana derived drugs, assurance that scientific innovation does not outpace Quality and Regulatory (QARA) guidelines is a concern for many.

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Posted in Articles, Ask Alconox, Biotechnology, Cannabis, Pharmaceutical, Quality/Regulatory0 Comments

Biopharma Cleaning: Hormone Residue

Q. How can I clean residual hormone residue from our process lines and tanks?
A. For manual cleaning we would highly recommend TergazymeⓇ Enzyme Active Powered Detergent. It contains protein enzymes that can effectively break down protein based hormones along with powerful emulsifiers.

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Posted in Alcojet, Biotechnology, Detojet, Detonox, Laboratory, Pharmaceutical, Tergazyme0 Comments