Archive | Biotechnology

Cannabis Residue Cleaning: Quality Assurance in the Lab

Q. We are working on the laboratory testing and production of several cannabis products. We’ve been working with Alconox, Inc. products for some time to effectively clean our labware, glassware and processing equipment. What types of cleaning-related quality issues can you provide guidance on?

A. The medical cannabis, cannabidiol, hemp and similar industries are increasing in scope and interest, across the U.S. and the globe. Your question is timely. With FDA approval of some marijuana derived drugs, assurance that scientific innovation does not outpace Quality and Regulatory (QARA) guidelines is a concern for many.

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Posted in Articles, Ask Alconox, Biotechnology, Cannabis, Pharmaceutical, Quality/Regulatory0 Comments

Biopharma Cleaning: Hormone Residue

Q. How can I clean residual hormone residue from our process lines and tanks?
A. For manual cleaning we would highly recommend TergazymeⓇ Enzyme Active Powered Detergent. It contains protein enzymes that can effectively break down protein based hormones along with powerful emulsifiers.

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Posted in Alcojet, Biotechnology, Detojet, Detonox, Laboratory, Pharmaceutical, Tergazyme0 Comments

Clean in Place “Hacks” for Water Spots

A: A two-step cycle with a base followed by an acid, whether it be CIP cleaning or in a large scale liquid dispensing system washer, is a robust and, when needed, is a recommended process. Water spots typically occur because of two main mechanisms….

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Posted in Biotechnology, Citrajet, Cosmetic, Laboratory, Medical Device, Metalworking & Precision Manufacturing, Pharmaceutical, Solujet0 Comments

Going Green with Cold Cleaning

Q: We are a large biotech and in an effort to go green with our cleaning, we are exploring cold cleaning (cleaning with cold water) using your detergents. A: Cold cleaning is a very reasonable approach for energy conservation, and in short, its effectiveness depends on the details of the application.

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Posted in Biotechnology, Cosmetic, Laboratory, Manual Lab Cleaning, Medical Device, Metalworking & Precision Manufacturing, Pharmaceutical0 Comments

Cleaning Stressed Polycarbonate

Q. In the past you have recommended a specific detergent type detergent for our sensitive plastics (stressed polycarbonate), mentioning that it does not have a surfactant. Can you elaborate for us why?

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Posted in Biotechnology, Cosmetic, Detojet, Medical Device, Pharmaceutical0 Comments

What is a Surfactant?

Q. What is a surfactant? A. Surfactant is short for “surface active agent,” it is an organic molecule with a hydrophobic (water-hating/oil-loving) end and a hydrophilic (water-loving) end.

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Posted in Biotechnology, Detergents, Laboratory, Medical Device, Pharmaceutical, Validation0 Comments

CIP

Static and Dynamic Spray Balls for Clean in Place

Q. What are the differences between Static and Dynamic spray balls in CIP machines? A. The typical considerations in using either static or dynamic spray balls in CIP (clean-in-place) are that….

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Posted in Biotechnology, Citrajet, Cosmetic, Pharmaceutical, SolujetComments Off on Static and Dynamic Spray Balls for Clean in Place

What to choose: acid vs alkaline cleaner?

Q:  What are the differences between an acid vs alkaline cleaner? A:  There are some key difference in choosing the right cleaner for your cleaning needs; the ph of a detergent is one dividing line. Acidic cleaners are commonly used to brighten or etch metals and are effective at removing any mineral deposits or oxidation […]

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Posted in Alconox, Biotechnology, Citrajet, Citranox, Medical Device, Metalworking & Precision Manufacturing, PharmaceuticalComments Off on What to choose: acid vs alkaline cleaner?

Advanced Cleaning Mechanisms: Detergency and Concentration

Intuition, logic, and maybe even some experiences, can lead us to believe more detergent is better.  These everyday experiences where it might apply include your washing machine, dishwasher, or even your hands in the bathroom sink.  But, what is actually meant by better?  This is where concentration and detergency come into play, terms you may see in our literature and documentation, as well as our responses and solutions to cleaning challenges.

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Posted in Articles, Biotechnology, Cosmetic, Electronic, Laboratory, Medical Device, Metalworking & Precision Manufacturing, Pharmaceutical0 Comments

How to: Remove Residual Silicone Oils

Q. We are currently using a solvent and we want to switch to a safer product, such as a water-based cleaner.  Do you have a detergent that can assist in the removal of residual silicone oils that are left in medical device mold inserts manufactured using clear rubber material?   Will Alconox detergent work as your web page says without ultrasonic?

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Posted in Alconox, Biotechnology, Medical Device, Pharmaceutical0 Comments