Archive | Biotechnology

Cleaning pH Probes & Dissolved Oxygen Probes

Q. Which Alconox Inc. brand cleaner is well suited for cleaning pH and dissolved oxygen probes?

A. Dissolved oxygen and pH probes used in fermentation vessels can get buildup from the fermentation media that degrades the probe performance and increases the likelihood of batch to batch contamination. Even CIP systems cannot always reliably clean the port crevices and o-rings.

Read the full story

Posted in Biotechnology, Food & Beverage, Laboratory, Tergazyme0 Comments

How to Choose a CIP Detergent

Meet cGMP regulations and stringent cleaning validation standards with CIP detergents from Alconox Inc. Whether you use single pass or recirculation systems, Alconox can provide a detergent ideally suited for your CIP system. Click to watch our latest video to learn best practices for Clean in Place and how to choose the right CIP detergent for your application.

Read the full story

Posted in Biotechnology, Cosmetic, Pharmaceutical, Quality/Regulatory, Video0 Comments

Cannabis Residue Cleaning: Quality Assurance in the Lab

Q. We are working on the laboratory testing and production of several cannabis products. We’ve been working with Alconox, Inc. products for some time to effectively clean our labware, glassware and processing equipment. What types of cleaning-related quality issues can you provide guidance on?

A. The medical cannabis, cannabidiol, hemp and similar industries are increasing in scope and interest, across the U.S. and the globe. Your question is timely. With FDA approval of some marijuana derived drugs, assurance that scientific innovation does not outpace Quality and Regulatory (QARA) guidelines is a concern for many.

Read the full story

Posted in Articles, Ask Alconox, Biotechnology, Cannabis, Pharmaceutical, Quality/Regulatory0 Comments

Biopharma Cleaning: Hormone Residue

Q. How can I clean residual hormone residue from our process lines and tanks?
A. For manual cleaning we would highly recommend TergazymeⓇ Enzyme Active Powered Detergent. It contains protein enzymes that can effectively break down protein based hormones along with powerful emulsifiers.

Read the full story

Posted in Alcojet, Biotechnology, Detojet, Detonox, Laboratory, Pharmaceutical, Tergazyme0 Comments

Ultrasonic with Low-Foam Detergent

Q. We are having foaming issues in ultrasonic cleaner. Basically, we are looking for a non-foaming version of the Liquinox cleaner we are currently using.  Can you use a detergent that doesn’t foam in an ultrasonic bath? A. Depending on what the foaming issue is, you may be able to continue using Liquinox detergent. As a general statement….

Read the full story

Posted in Biotechnology, Healthcare, Laboratory, Liquinox, Manual Lab Cleaning, Medical Device, Pharmaceutical, Solujet0 Comments

BRK Cleanroom

Cleanroom Cleaning

We are in the process of building a cleanroom for medical device manufacturing. What detergents do you recommend? For cleanroom cleaning, we would recommend liquid concentrate detergents to…..

Read the full story

Posted in Biotechnology, Liquinox, Manual Lab Cleaning, Medical Device, Pharmaceutical0 Comments

Clean in Place “Hacks” for Water Spots

A: A two-step cycle with a base followed by an acid, whether it be CIP cleaning or in a large scale liquid dispensing system washer, is a robust and, when needed, is a recommended process. Water spots typically occur because of two main mechanisms….

Read the full story

Posted in Biotechnology, Citrajet, Cosmetic, Laboratory, Medical Device, Metalworking & Precision Manufacturing, Pharmaceutical, Solujet0 Comments

Going Green with Cold Cleaning

Q: We are a large biotech and in an effort to go green with our cleaning, we are exploring cold cleaning (cleaning with cold water) using your detergents. A: Cold cleaning is a very reasonable approach for energy conservation, and in short, its effectiveness depends on the details of the application.

Read the full story

Posted in Biotechnology, Cosmetic, Laboratory, Manual Lab Cleaning, Medical Device, Metalworking & Precision Manufacturing, Pharmaceutical0 Comments

Cleaning Stressed Polycarbonate

Q. In the past you have recommended a specific detergent type detergent for our sensitive plastics (stressed polycarbonate), mentioning that it does not have a surfactant. Can you elaborate for us why?

Read the full story

Posted in Biotechnology, Cosmetic, Detojet, Medical Device, Pharmaceutical0 Comments

What is a Surfactant?

Q. What is a surfactant? A. Surfactant is short for “surface active agent,” it is an organic molecule with a hydrophobic (water-hating/oil-loving) end and a hydrophilic (water-loving) end.

Read the full story

Posted in Biotechnology, Detergents, Laboratory, Medical Device, Pharmaceutical, Validation0 Comments