Using pH and Conductivity to Detect Residues

Q. We are in the process of developing a cleaning validation study for our laboratory glassware. The cleaning agent selected was Alconox. We are trying to establish acceptance criteria using the pH method to ensure successful removal of the cleaning agent. We did some trials using a solution made with mixtures of the Di water, which is 1000 ppm to see what it looks like but the results were not clear to me. How about the other method as conductivity?

A. Thanks for your request for information about using pH and conductivity to detect residues of Alconox. A dilution of 0.01 would not be sufficient to significantly lower the pH of an Alconox solution. Alconox is buffered.

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