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Tergazyme and Alconox
Published: August 17, 2020

Q: What is the difference between Tergazyme and Alconox?  Is one better?  Is one more mild?

A: There are several similarities and key differences between Tergazyme® Enzyme-Active Powdered Detergent and Alconox® Powdered Precision Cleaner.  Both detergents are powerful emulsifiers and excellent detergents for the removal of organic and oily residues.  Both detergents are well suited for use in ultrasonic baths, or other forms of manual cleaning including scrubbing and soaking.  They are both mild alkaline cleaners (pH 9.5) in a powdered detergent format.  Tergazyme and Alconox detergents have a shelf life of the undiluted powder of 2 years.  The detergents are free-rinsing, interfering residue-free and biodegradable, with no added dyes, fragrances, brighteners or softeners.

Tergazyme detergent does have the added benefit of proteolytic enzymes which greatly assist in the removal of bioresidues and fluids including blood, tissue and other proteinaceous contaminants.  Due to the presence of these enzymes, unlike Alconox detergent, the Tergazyme wash solution should be kept below 130F/55C to avoid enzyme degradation.  (Alconox detergent solutions can and have been used up to boiling temperatures.)  Additionally, Tergazyme solutions should be used within 8 hours to avoid autocatalysis, as after all, the enzymes are made of proteins.  This also explains why Tergazyme has such a high effective shelf life compared to liquid enzymatic detergents.

While both would do a great job in applications including cleaning and reprocessing of medical devices, and other parts exposed to biologic residue, Tergazyme cleaner gives an extra edge.  This includes tattoo and healthcare applications where parts are to be cleaned and disinfected between uses.

We’d love to discuss how Tergazyme detergent may be of use in your particular application.  In the meantime, review the video!

To request these or any Alconox Inc. detergents for free, please complete the questionnaire at Get Sample. For more information about any one of our Alconox Inc. detergents, consult the technical bulletin for each product. Or click here to access each of our detergent’s Safety Data Sheets.

Do you have a critical cleaning question for the experts at Alconox Inc.?  Search TechNotes to see if it’s been answered before or Ask Alconox.

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4 responses to “Tergazyme vs. Alconox”

  1. Paul Mink says:

    How is Tergazyme rinsed completely off of a surface or equipment? Is there any kind of neutralizing agent required?
    Thank you.
    Paul Mink

  2. GBrown says:

    I use Tergazyme continuously and flawlessly. I have come upon a situation where there is a person highly reactive to odors and chemicals so it is causing strong hesitancy in cleaning in their environment.
    Question: If I clean with Tergazyme, rinse, and then come back over it using vinegar afterward should it neutralize any odor or after-smells? I want to clean it thoroughly and avoid setting off a medical-health issue.

    • Anonymous says:

      Thank you for your inquiry. Tergazyme detergent rinses completely away and will leave no residues behind. There should not be any scent or after-smells. It is a free-rinsing detergent. As indicated above, please contact for a more detailed inquiry.

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