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Cleaning Bioreactors

Q. How can I clean bioreactors and do you have any SOPs you can offer.
A. Liquinox is typically used for cleaning bioreactors. A 1% solution of Liquinox (1.25 oz/gal or 10 mL/L) is used to soak and scrub the bioreactor. Learn More.

Health and Safety Considerations for Medical Device Cleaners

Q. What are health and safety considerations when selecting and using a medical device cleaning agent?
A. Human health and safety considerations include detergent toxicity, corrosivity, reactivity, and flammability. These considerations can be evaluated by reviewing a Safety Data Sheet for the solvent, chemical, or detergent with which you intend to clean. Learn More.

Cleaning Machined PTFE Parts

Q. I just received your chapter on cleaning SOPs and I look forward to reading it. In parallel, I was hoping to get your thoughts or a bit of advice on how to create and implement cleanliness specifications/processes for machined (PTFE) plastic parts. Cutting fluid for the machining center is basically a water soluble vegetable oil-based fluid. The use of this plastic manifold and cover is within an electro-mechanical-fluidic subsystem (“Delivery Module”). This delivery module accumulates a quantity of 59wt% Hydrogen Peroxide that has been … Click to Read The Full Question and Answer.

Cleaning Liquid Residue on Pipet Walls

Q. We are doing some experiments to quantify the amount of liquid residue on pipet walls before/ after cleaning. In practise, this would relate the accuracy of the pipet to its cleanliness. Could you inform us if the use of Alconox affects the amount of beading (of distilled water) on the walls of a brush cleaned and rinsed pipette, compared with the use of common dishwashing liquid?

A. Proper cleaning of a pipet will result in the designed amount of fluid being measured in a pipet according designed amount of beading resulting from the correct clean surface energy of the pipet and the surface tension of the fluid being measured. Typically pipets . . .

Optical Lens Cleaning

Q. How do you clean wax marks on optical lenses which are difficult to remove?
A. Use either 1% Alconox or Liquinox in a heated 160 deg F ultrasonic bath followed by a deionized water rinse to clean optical lenses during manufacturing.

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