Our CIP system is struggling with a new product leaving drug residues of magnesium oxide and calcium silicate. We recently switched from a competitor to Solujet which worked very well but not on this newest product. What should we be doing?
Q: I am contacting you to ask for more info regarding the stability of Tergazyme as we encountered a temperature deviation during shipment. The exposure temperature was 47C for about 3 hours.
A: Dry powdered Tergazyme® Enzyme-Active Powdered Detergent will be fine with a 3-hour excursion to….
Q: Do you have usable detergents above boiling temperature? Any that we could consider that could withstand such high temps?
A: Great question. There are several uses currently in play across many industries where detergents are used at or near boiling temperatures.
For use of detergents above the boiling point, a couple of factors need to be discussed.
We are a large pharma company. We use Alconox detergent in an ISO 8 cleanroom that does not have a floor drain so rinsing in a cleanroom is a problem. We have a form, fill, seal machine with 2 pumps, tubing, and a hopper that have product contact. They are permanently installed. Can we rinse with tap water if we are sanitizing after the rinse? How much rinsing is required?
Q. I’ve been told that we should no longer use isopropyl alcohol for cleaning our pharmaceutical equipment. What should we use instead?
A. In pharmaceutical cleaning applications, isopropyl alcohol (IPA) is less than ideal. Alcohol will clean residues which are soluble in alcohol, but that is a limited range. Using critical cleaning, aqueous detergents are a far more robust and will allow for more effective cleaning processes.
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For further assistance please fill out the form at Ask Alconox or email us at cleaning@alconox.com.