Removing Eudragit from Equipment
Eudragit brand coloring agents from Roehm GmbH & Co for coating tablets can be very difficult to clean from tablet coating equipment. Different Eudragits need different types of cleaning agents. Some require acid cleaners with wetting agents and dispersants, and some require alkaline cleaners with wetting agents and dispersants.
Why is there no Liquid Tergazyme?
Q. Is there a liquid equivalent to Tergazyme® enzyme-active powdered detergent?
A. There is not a liquid equivalent to Tergazyme detergent. Liquid products do not give comparable shelf life and robust, reliable enzymatic activity compared to powders like Tergazyme detergent.
Types of Aqueous Cleaners
Q. What are the different types of aqueous cleaners? A. Alconox, Inc. manufactures aqueous cleaners in acid, neutral, mild alkaline and corrosive alkaline for use in various critical cleaning applications.
Pharmaceutical Cleaning Validation for FDA Code
Q. What part of the FDA Code of Federal Regulations applies to cleaning equipment?
A. The FDA Code of Federal Regulations 21 CFR 211.67 applies to equipment cleaning and maintenance. If you are cleaning pharmaceutical equipment with Alconox brand cleaners, our team of experts can assist you in your cleaning validation.
Max Concentration for Tergazyme
Q: When using Tergazyme® enzyme-active powdered detergent, the recommended concentration is 1%. Are there occasions when a greater concentration is used? If so, is there some kind of saturation point where a high concentration will be ineffective?
A: Tergazyme detergent has a solubility limit around 10% (w/w) in water depending on temperature.