Liquid Soda Ash to Neutralize Citranox
Q. We’re using Citranox in our laser chillers. Looking for liquid soda ash to remove the Citranox?
Plastic Soak Containers for Cleaning
Q. What kind of plastic container can I use to hold a detergent soak solution?
You can use any container that is robust enough to hold typical aqueous solutions of chemicals. A polypropylene or other chemical resistant plastic container such as HDPE will work just fine for cleaning.
Setting Residue Acceptance Criteria
Q. Do you have to set residue acceptance criteria for cleaners?
A. Yes. For pharmaceutical and medical device manufacturing it is required that there be set residue acceptance levels for potential residues such as the active drug, excipients, degradation products, cleaning agents, bioburden and endotoxins.
Effects of Increased Tergazyme Concentration
Q. Currently we allow parts to soak in 1% Tergazyme® enzyme-active powdered detergent overnight. If we were to increase the concentration to 3-4%, do you think it would increase the stability of the solution being active for a longer period of time?
A. You will both increase the rate of auto-digestion due to increased enzyme concentration
Removing Eudragit from Equipment
Eudragit brand coloring agents from Roehm GmbH & Co for coating tablets can be very difficult to clean from tablet coating equipment. Different Eudragits need different types of cleaning agents. Some require acid cleaners with wetting agents and dispersants, and some require alkaline cleaners with wetting agents and dispersants.
