Tag Archive | "CIP"

Removing Protein in Pharmaceutical and Biotech Manufacturing

Q. How do you remove protein out of pipes, centrifuges and tanks in a CIP environment with water temperatures averaging 20C?

A. In a cooler temperature environment, consider adding an enzymatic cleaner to your alkaline/acidic CIP routine. A product like Tergazyme® Enzyme-Active Powdered Detergent, which contains both protease and surfactants, is not only efficient at removing the biofilm, but will also slow down the formation of biofilm and allow the regular cleaning cycle to clean effectively for more cycles.

Read the full story

Posted in Biotechnology, Pharmaceutical, TergazymeComments (0)

Clean-in-place (CIP) with Citrajet Detergent

Q. Our pharmaceutical company is transferring product manufacture to a different one our facilities. We used a CIP cleaning process with Citrajet and are going to have to perform validation and verification tests again. What information do we need for our testing? Chemical properties might be helpful as well as the science on how this chemical works. We would also need information on disposal and the requirements for allowing this to flow to normal process drains.

Read the full story

Posted in Citrajet, Keylajet, Pharmaceutical, Solujet, ValidationComments (0)

Keylajet

What is Keylajet detergent?

We’ve been a long time user of Solujet for our CIP system, and love it! I recently passed by your booth at a tradeshow and you set me up with a sample of Keylajet when we mentioned some extra viscous waxy residue we were having trouble removing. We were hoping to stay with our CIP method. It worked great! Can you relay more info?

Read the full story

Posted in Cosmetic, Detonox, Keylajet, Pharmaceutical, SolujetComments (0)

Solution Preparation Tank

Cleaning Titanium Dioxide from Tanks

Residual titanium dioxide (TiO2) can certainly pose issues due to it’s nature in the presence of heat. To remove TiO2 from tanks using CIP sprayballs, it is important to use….

Read the full story

Posted in Biotechnology, Cosmetic, Keylajet, Pharmaceutical, SolujetComments (0)

CIP

How much CIP detergent needed?

Q: We are starting a new bioprocessing facility where we will be cleaning stainless steel tanks via a Clean-In-Place sprayball system? How do I approximate how much detergent I will need? We are considering Alcojet or Solujet, follow by an acidic rinse with Citrajet. Is this a good plan? Any advice? A: A good rule of thumb for tis you need about….

Read the full story

Posted in Biotechnology, Citrajet, Cosmetic, Keylajet, Pharmaceutical, SolujetComments (0)

http://www.wves.org/environmentally-friendly-choice-electronic-cigarette

Cleaning E-cigarette Manufacturing Equipment

We are manufacturing e-cigarettes and need to find a good cleaner for our equipment. We are removing residues of essential oils, glycerin and flavor enhancers with an automated clean-in-place. Our tank is 500 gallons. We are unsure how much cleaner we need. Can you at Alconox Inc. help? We would recommend hot Solujet detergent. Learn more…

Read the full story

Posted in Pharmaceutical, SolujetComments (0)

Pharma Ointment Residue via CIP

Q. We are a generic pharmaceutical manufacturer of Creams and Ointments. We are having difficulty cleaning equipment (specifically CIP) after making these types of products. We have been successful in cleaning 95% of our products using the alkaline detergent. We have couple of products that leave a white film after the cleaning cycles. These products do not contain metal oxides. We are planning to try the Citranox acid cleaner. Any suggestions?

Read the full story

Posted in Citrajet, Citranox, PharmaceuticalComments (0)

Solujet detergent for CIP in Pharmaceutical Industry

Solujet cleaner is the detergent to consider for your next new pharmaceutical cleaning project or when you want to take the opportunity to improve when you are revalidating your existing cleaning system.

Read the full story

Posted in Biotechnology, Pharmaceutical, SolujetComments (0)

Addition of Acid Rinse to Wash Cycle

We have a glass wash machine and use Alcojet for it. We would like to know if you need to include a neutralizing agent like Citrajet as part of the wash cycle (acid rinse)? Alcojet® Low Foaming Powdered Detergent is what we would call free-rinsing, meaning it rinses completely away with water without rinse aids.

Read the full story

Posted in Alcojet, Ask Alconox, Biotechnology, Citrajet, Laboratory, Medical Device, PharmaceuticalComments (0)

How does Solujet stack up to a leading CIP cleaner?

How does Solujet stack up to a leading CIP cleaner?

Unlike A LEADING CIP CLEANER, Solujet has high wetting surfactants that enhance emulsifying, wetting, dispersing and rinsing. The surfactants allow faster, more efficient cleaning and easier rinsing.

Read the full story

Posted in Biotechnology, Cosmetic, Pharmaceutical, SolujetComments (0)