Q: We are starting a new bioprocessing facility where we will be cleaning stainless steel tanks via a Clean-In-Place sprayball system. How do I approximate how much CIP detergent I will need per tank? We are considering Alcojet or Solujet, follow by an acidic rinse with Citrajet. Is this a good plan? Any advice? A: A good rule of thumb we use is you need about 10% of the … [Read more...] about How much CIP detergent needed?
Q. Your website and literature often describes your detergents as free rinsing. What does free rinsing detergent mean? A. A free rinsing detergent means it will rinse away very easily or freely. This is vital to critical cleaning applications. Analytical glassware, medical device implants or biopharm process lines are just a few examples where clean, residue-free surfaces … [Read more...] about Defining Free Rinsing Detergent
Q: How can we clean residual deodorant from our stainless steel tanks? It is proving very difficult. It is largely AlCl3. A: Deodorant, designed to stay in place for obvious reasons, can be quite adherent on processing equipment. If it stays on skin for extended periods, which is designed to avoid residues, imagine what it does to stainless steel! As deodorants are … [Read more...] about Cosmetics Cleaning: Removing Deodorant From Stainless Tanks
Q. How can I clean proteins, RNA and DNA from laboratory equipment? A. Thank you for your question concerning cleaning proteins, RNA and DNA from laboratory equipment. I will address each separately as the best way to clean proteins, RNA and DNA would be three separate methods : 1) For the removal of protein our recommendation is Tergazyme® Enzyme-Active Powdered Detergent. … [Read more...] about Cleaning Proteins, RNA and DNA from Lab Equipment
Q. Our pharmaceutical company is transferring product manufacture to a different one of our facilities. We used a CIP cleaning process with Citrajet detergent and are going to have to perform validation and verification tests again. What information do we need for our testing? Chemical properties might be helpful as well as the science on how this chemical works. We would also … [Read more...] about Clean in place (CIP) with Citrajet Detergent