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Microfluidics

How to: Clean a Microfluidics System

Q: We are looking for a cleaning solution to remove sodium contamination to a sub ppt level from a microfluidics system. Can Alconox Inc. help?

A: Microfluidics is the field of accurately and precisely transporting small amounts of liquid.  This requires small channels which can be a challenge to clean. To remove inorganic residues from a narrow ID system, we would want to use a low foaming detergent….

stainless steel large tank

Cleaning of Rouge and Passivation of Stainless

Q: We have a stainless steel large tank a piping system with rouge cleaning and passivation needs. Requiring a low foaming detergent, as we will run a CIP system. Can Alconox Inc. assist?

A: Rouge is the formation of iron oxide or hydroxide on stainless steel, often created by a corrosive over time or improper passivation efforts.   To clean rouge we recommend a hot (65C / 150F or hotter) 3%….

Reverse osmosis system

How to: Tergazyme Enzyme Deactivation

Q: We have started using Tergazyme for our filter cleaning application and it is working great. What would you recommend for Tergazyme enzyme deactivation?

A: Realistically speaking the enzyme will get deactivated by

CIP detergent

How much CIP detergent needed?

Q: We are starting a new bioprocessing facility where we will be cleaning stainless steel tanks via a Clean-In-Place sprayball system? How do I approximate how much detergent I will need? We are considering Alcojet or Solujet, follow by an acidic rinse with Citrajet. Is this a good plan? Any advice? A: A good rule of thumb for tis you need about….

biotech centrifuge

Cleaning Guanidine Thiocyanate and Sodium Azide

Q: What do you recommend to clean guanidine thiocyanate and sodium azide from a centrifuge.  The centrifuge manufacturer requests a low foaming neutral cleaner. There may also be enzymatic residues.

A: To remove salts like guanidine thiocyanate and sodium azide, and other inorganics, we would normally recommend

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