critical cleaning advice from Alconox Inc.

biopharma

How to Choose a CIP Detergent

Meet cGMP regulations and stringent cleaning validation standards with CIP detergents from Alconox Inc. Whether you use single pass or recirculation systems, Alconox can provide a detergent ideally suited for your CIP system. Click to watch our latest video to learn best practices for Clean in Place and how to choose the right CIP detergent for your application. Alconox CIP … [Read more...] about How to Choose a CIP Detergent

How much CIP detergent needed?

Q:  We are starting a new bioprocessing facility where we will be cleaning stainless steel tanks via a Clean-In-Place sprayball system.  How do I approximate how much CIP detergent I will need per tank?  We are considering Alcojet or Solujet, follow by an acidic rinse with Citrajet. Is this a good plan?  Any advice? A: A good rule of thumb we use is you need about 10% of the … [Read more...] about How much CIP detergent needed?

Biopharma Cleaning: Hormone Residue

Q: How can I clean residual hormone residue from our process lines and tanks? A: For manual cleaning we would highly recommend TergazymeⓇ Enzyme Active Powered Detergent.  It contains proteolytic enzymes that can effectively break down protein based hormones, along with powerful emulsifiers.  For a liquid concentrate manual cleaner, I would certainly recommend DetonoxⓇ … [Read more...] about Biopharma Cleaning: Hormone Residue

Cleaing Protein in Pharmaceutical and Biotech Manufacturing

Q. How do you clean protein out of pipes, centrifuges and tanks in a recirculation CIP environment with water temperatures averaging 20°C? A. In a cooler/ambient temperature environment, protein cleaning and removal can certainly be tough.  After all, heat expedites cleaning.  Consider adding an enzymatic cleaner to your alkaline/acidic cleaning routine. A product like … [Read more...] about Cleaing Protein in Pharmaceutical and Biotech Manufacturing