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Cleaning Vitamin Residues

Q. We manufacture vitamins, which include minerals (calcium, magnesium etc.) and have found that Citranox is very effective in cleaning the residue left in our equipment. Unfortunately, we have learned that the pH of Citranox is too low for our local requirements. Do you have another detergent with a higher pH that would work equally as well?

Manual Cleaning A 100 Gallon Mixer

Q: We are looking for detergent and process recommendations for manual cleaning of a 100 gallon mixer. We make one product in the mixer which contains water, starch, acidic buffers, sucralose and preservative. Currently when cleaning, we boil for 1 hour at 90°C, then cool, drain and soak in cool water while using the mixing blades.  Scrub brushes and a spray hosing follows that. The mixer is made from stainless steel.

Clean in place (CIP) with Citrajet Detergent

Q. Our pharmaceutical company is transferring product manufacture to a different one our facilities. We used a CIP cleaning process with Citrajet and are going to have to perform validation and verification tests again. What information do we need for our testing? Chemical properties might be helpful as well as the science on how this chemical works. We would also need information on disposal and the requirements for allowing this to flow to normal process drains.

Pharmaceutical Cleaning: Choosing CIP Detergent  

Equipment used in pharmaceutical manufacturing must be cleaned before each use, and the cleaning procedure used must be in accordance with good manufacturing practices (GMPs). There are different types of CIP including, single pass systems and recirculation system. No matter which type is used, Alconox, Inc. provides support to meet cGMP regulations and detergents ideally suited for CIP systems.

Pharmaceutical Cleaning: Probiotics

Q: Can you tell me if Liquinox can clean/remove pharmaceutical probiotics? We use this product to clean our packaging lines. We have a customer who is looking to have us package their probiotic product.

A: Liquinox® Critical Cleaning Liquid Detergent is an excellent emulsifier of organic and oily residues. It will do the job. Best practice, however, would be to incorporate a powerful emulsifier of organic and oily residues, along with enhanced protein removal. 

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For further assistance please fill out the form at Ask Alconox or email us at cleaning@alconox.com.