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residue detection

Laboratory Cleaning: Eliminating Residual Nitrogen

August 8, 2019

Q. I am setting up a scientific analytical lab and wondering which of your liquid cleaning solutions is free of both phosphorus and nitrogen?  A. Sounds like your concern is residual nitrogen for analysis purposes as opposed to containing elemental nitrogen. In that case, as we do for many, we recommend Liquinox® Critical Cleaning Liquid Detergent. Analytical, … [Read more...] about Laboratory Cleaning: Eliminating Residual Nitrogen

Residue Detection: Swab Method

February 26, 2019

Q. Do you have a recommended swab detection method for residual detergent? A. We most certainly do.  It is suggested to use a swabbing area of 5 cm X 5 cm. Where extreme low level acceptance criteria on a low recovery residue, i.e. some product residues, it can help to use a 10X10 cm area. However, for detergent residues, you should not have to go to a 10X10 cm area in order … [Read more...] about Residue Detection: Swab Method

Risk Based Limits and Pharmaceutical Cleaning

June 21, 2018

Q. We are moving from LD50 data to ADE (PDE) limits based on HBELs. This is allowing us to eliminate disposables for low-risk products.  How do I know which can be manually cleaned and which needs to be in a washer? Can manual cleaning be validated? A. Many pharma and biotech companies have been moving to Health-Based Exposure Limits (HBELs) meaning Acceptable Daily Exposure … [Read more...] about Risk Based Limits and Pharmaceutical Cleaning

Perchlorate Free Detergents

May 22, 2018

Q. We are looking for a laboratory dishwasher detergent that does not contain perchlorates. One of our end users analyzes for trace levels of perchlorates, so we cannot have a detergent that has that type of impurities. A. None of our detergents contain perchlorates.  However, perchlorates can be a very trace contaminant in phosphate containing detergents, even if the … [Read more...] about Perchlorate Free Detergents

Detecting Residue in Cleaning Validation

June 15, 2017

When beginning cleaning validation, a company must identify the residues to be tested and then select the best detection method. Alconox Inc. is here to help.  We provide validation guidance and we also provide technical support via Downloadable Whitepapers. Here is an excerpt about Identifying Residue and Selecting a Detection Method: Before you start identifying … [Read more...] about Detecting Residue in Cleaning Validation

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