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closed bioprocessing

Closed Bioprocessing Cleaning Recommendations

Q: We are a mid sized small biomolecule drug manufacturer and currently use several Alconox, Inc. products in our cleanroom and manufacturing suites.  We are looking at implement (functionally) closed bioprocessing.  Are there any recommendations you can provide?
A: Some time ago, I heard a senior executive of a large biotech company express a desire to produce drugs in a “conference room.”  That day is pretty much here. 

Defining Free Rinsing Detergent

A non-free rinsing cleaner might contain fragrances that were designed to deposit and leave a fresh scent, or it might contain corrosion inhibitors that are designed to deposit and leave behind an anti-corrosion film.

Alconox, Inc, cleaners are free rinsing detergents and do not leave deposits on substrates after rinsing.

Cleaning Vitamin Residues

Q. We manufacture vitamins, which include minerals (calcium, magnesium etc.) and have found that Citranox is very effective in cleaning the residue left in our equipment. Unfortunately, we have learned that the pH of Citranox is too low for our local requirements. Do you have another detergent with a higher pH that would work equally as well?

Glassware and Utensils Came Out Coated In A Dry White Residue

Q: We are working with a lab washer in a compounding pharmacy application. We are using Detergent 8 to clean glassware and utensils. The glassware and utensils came out coated in a dry white residue. Can you please advise why this is happening with this detergent?

Do Enzymatic Detergents Disinfect?

Q. We have been using Tergazyme to clean lenses and cuvettes for our light scattering equipment and it works flawlessly! My question is: Does Tergazyme enzyme detergent have any disinfection properties, like killing of bacteria such as E. coli, or viruses?

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