We run our caustic cleaning at pH 10-10.5. However, the specifications say the nominal pH of a 1% Tergazyme solution is 9.5 Are we compromising cleaning proteins / enzyme performance by using the higher pH and running as part of a caustic cycle? Can we run it at 110F or should we be lower?
Q. We reprocess single use medical devices and we are having trouble getting organic and biological residue out of crevices. It is requiring cleaning for a much longer time than we can support in our processes. We’ve started to do pre-soaking as we read that this would help, but we’re a little concerned we are not doing that optimally either. Can you make recommendations?
Q. We use Tergazyme to clean our TFF cassettes and it’s working well. However, we are moving to CIP cleaning in an automated, high pressure environment and are worried about foaming. Do we stick with Tergazyme or is there a better detergent we should use?
A. Tergazyme® Enzyme-Active Powdered Detergent is of an excellent choice for cleaning TFF cassettes. Even as you move to more high pressure, automated CIP method, Tergazyme detergent will likely continue to work well. That’s because….
Clean laboratory glassware is essential in all laboratories. No scientist, engineer, laboratory technician, or analyst has time to fail an experiment because of contaminated glassware.
Good, well-built, precision detergents (like the Alconox, Inc. portfolio of course) can make up for quite of bit incomplete, inefficient or incorrect glassware cleaning techniques.
Q. How can Alconox detergents assist with our movement to continuous bioprocessing? A: Continuous bioprocessing is an exciting newcomer to the biotech realm. It has been used in industries such as food and chemicals for some time, effectively so. With improvements in cell culture perfusion, and the many forms of disposable technologies on the market, footprints can be reduced making continuous processing for biotech products a reality for many applications.
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